{"id":39252,"date":"2026-07-28T09:20:41","date_gmt":"2026-07-28T05:50:41","guid":{"rendered":"https:\/\/abtaab.ir\/?p=39252"},"modified":"2026-08-04T00:08:53","modified_gmt":"2026-08-03T20:38:53","slug":"%d9%86%d8%b8%d8%a7%d9%85-%d9%85%d9%84%db%8c-%d8%a7%d8%b1%d8%b2%db%8c%d8%a7%d8%a8%db%8c-%d9%81%d9%86%d8%a7%d9%88%d8%b1%db%8c-%d8%b3%d9%84%d8%a7%d9%85%d8%aa-hta-%d9%88-%d8%aa%d8%b5%d9%85%db%8c%d9%85","status":"publish","type":"post","link":"https:\/\/abtaab.ir\/?p=39252","title":{"rendered":"\u0646\u0638\u0627\u0645 \u0645\u0644\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a (HTA) \u0648 \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 14pt; color: #0000ff;\"><strong><a style=\"color: #0000ff;\" href=\"https:\/\/www.abtaab.ir\/\">\u0622\u0628\u062a\u0627\u0628<\/a>: <\/strong><span style=\"color: #000000;\">\u0627\u0646\u062f\u06cc\u0634\u06a9\u062f\u0647 \u0639\u0644\u0645\u06cc \u062a\u062d\u0642\u06cc\u0642\u0627\u062a\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0641\u0631\u0627 \u062f\u0642\u06cc\u0642 \u0622\u0646\u0627\u0628\u06cc\u062a\u0627\u0698\u0646\u060c \u0628\u0627 \u0647\u062f\u0641 \u062a\u0648\u0633\u0639\u0647 \u0633\u06cc\u0627\u0633\u062a\u200c\u06af\u0630\u0627\u0631\u06cc \u0639\u0644\u0645\u06cc\u060c \u0627\u0631\u062a\u0642\u0627\u06cc \u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a \u0648 \u06af\u0633\u062a\u0631\u0634 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646\u060c \u0628\u0647 \u062a\u0648\u0644\u06cc\u062f \u0648 \u0627\u0646\u062a\u0634\u0627\u0631 \u067e\u0698\u0648\u0647\u0634\u200c\u0647\u0627\u06cc \u0631\u0627\u0647\u0628\u0631\u062f\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u0645\u06cc\u200c\u067e\u0631\u062f\u0627\u0632\u062f. \u0627\u06cc\u0646 \u0627\u0646\u062f\u06cc\u0634\u06a9\u062f\u0647 \u0628\u0627 \u062a\u0645\u0631\u06a9\u0632 \u0628\u0631 \u0647\u0645\u200c\u0627\u0641\u0632\u0627\u06cc\u06cc \u0645\u06cc\u0627\u0646 \u067e\u0698\u0648\u0647\u0634\u060c \u0641\u0646\u0627\u0648\u0631\u06cc\u060c \u0627\u0642\u062a\u0635\u0627\u062f \u0633\u0644\u0627\u0645\u062a \u0648 \u0633\u06cc\u0627\u0633\u062a\u200c\u06af\u0630\u0627\u0631\u06cc \u0639\u0645\u0648\u0645\u06cc\u060c \u062f\u0631 \u062a\u0644\u0627\u0634 \u0627\u0633\u062a \u062a\u0627 \u0686\u0627\u0631\u0686\u0648\u0628\u200c\u0647\u0627\u06cc\u06cc \u0639\u0644\u0645\u06cc \u0648 \u0639\u0645\u0644\u06cc\u0627\u062a\u06cc \u0628\u0631\u0627\u06cc \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0646\u0648\u0622\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u062f\u0631 \u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a \u06a9\u0634\u0648\u0631 \u0627\u0631\u0627\u0626\u0647 \u062f\u0647\u062f. <\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 14pt; color: #000000;\">\u062f\u0631 \u0647\u0645\u06cc\u0646 \u0631\u0627\u0633\u062a\u0627\u060c \u0645\u0642\u0627\u0644\u0647 \u062d\u0627\u0636\u0631 \u0628\u0627 \u0639\u0646\u0648\u0627\u0646 \u00ab\u0646\u0638\u0627\u0645 \u0645\u0644\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a (HTA) \u0648 \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646: \u0686\u0627\u0631\u0686\u0648\u0628 \u062d\u0627\u06a9\u0645\u06cc\u062a\u06cc\u060c \u0638\u0631\u0641\u06cc\u062a\u200c\u0633\u0627\u0632\u06cc \u0648 \u067e\u06cc\u0648\u0646\u062f \u0628\u0627 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u200c\u0627\u06cc \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646 \u0645\u06cc\u200c\u067e\u0631\u062f\u0627\u0632\u062f \u0648 \u0631\u0627\u0647\u06a9\u0627\u0631\u0647\u0627\u06cc\u06cc \u0628\u0631\u0627\u06cc \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u062f\u0631 \u0627\u06cc\u0646 \u062d\u0648\u0632\u0647 \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><span style=\"font-size: 14pt;\"><strong>\u0639\u0646\u0648\u0627\u0646: <\/strong><\/span><strong>\u0646\u0638\u0627\u0645 \u0645\u0644\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a<\/strong><strong> (HTA) <\/strong><strong>\u0648 \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646: \u0686\u0627\u0631\u0686\u0648\u0628 \u062d\u0627\u06a9\u0645\u06cc\u062a\u06cc\u060c \u0638\u0631\u0641\u06cc\u062a\u200c\u0633\u0627\u0632\u06cc \u0648 \u067e\u06cc\u0648\u0646\u062f \u0628\u0627 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u200c\u0627\u06cc<\/strong><\/span><\/p>\n<h2 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><span style=\"font-size: 14pt;\">\u0646\u0648\u06cc\u0633\u0646\u062f\u06af\u0627\u0646:<\/span> <strong>\u062f\u06a9\u062a\u0631 \u0645\u062d\u0645\u062f \u0639\u0644\u06cc \u0635\u0627\u0631\u0645\u06cc<sup>*<\/sup>\u060c<\/strong><strong> \u062f\u06a9\u062a\u0631 \u0641\u0627\u0637\u0645\u0647 \u0645\u0647\u0633\u0627 \u06a9\u0627\u0631\u0622\u0645\u0648\u0632\u06cc\u0627\u0646<\/strong><strong><sup>*<\/sup><\/strong><strong>\u060c<\/strong><strong> \u0641\u0631\u0646\u0648\u0634 \u0647\u0646\u0631\u0645\u0646\u062f\u060c \u0645\u06cc\u062a\u0631\u0627 \u0634\u0645\u0633\u06cc\u0646\u06cc \u063a\u06cc\u0627\u062b\u0648\u0646\u062f<\/strong><strong>\u060c<\/strong><strong> \u0648 \u0646\u062c\u0645\u0647 \u0634\u062c\u0627\u0639\u06cc<\/strong><\/span><\/h2>\n<p><span style=\"font-size: 12pt; color: #000000;\"><strong><sup>* \u0627\u0646\u062f\u06cc\u0634\u06a9\u062f\u0647 \u0639\u0644\u0645\u06cc \u062a\u062d\u0642\u06cc\u0642\u0627\u062a\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0641\u0631\u0627\u062f\u0642\u06cc\u0642 \u0622\u0646\u0627\u0628\u06cc\u062a\u0627\u0698\u0646<\/sup><\/strong><\/span><\/p>\n<h2><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0686\u06a9\u06cc\u062f\u0647<\/strong><\/span><\/h2>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u0628\u0627 \u062a\u06a9\u06cc\u0647 \u0628\u0631 \u062f\u0627\u062f\u0647\u200c\u0647\u0627\u06cc \u0698\u0646\u0648\u0645\u06cc\u060c \u0628\u06cc\u0648\u0645\u0627\u0631\u06a9\u0631\u0647\u0627 \u0648 \u062f\u0631\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f\u060c \u062a\u062d\u0648\u0644\u06cc \u0628\u0646\u06cc\u0627\u062f\u06cc\u0646 \u062f\u0631 \u0646\u0638\u0627\u0645\u200c\u0647\u0627\u06cc \u0633\u0644\u0627\u0645\u062a \u062c\u0647\u0627\u0646 \u0627\u06cc\u062c\u0627\u062f \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a. \u0628\u0627 \u0627\u06cc\u0646 \u062d\u0627\u0644\u060c \u0647\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u0628\u0627\u0644\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635\u200c\u0647\u0627 \u0648 \u062f\u0631\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0634\u062e\u0635\u06cc\u200c\u0634\u062f\u0647 \u0648 \u0648\u0631\u0648\u062f \u0633\u0631\u06cc\u0639 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0648\u06cc\u0646 \u0628\u0647 \u0628\u0627\u0632\u0627\u0631\u060c \u0646\u0638\u0627\u0645\u200c\u0647\u0627\u06cc \u0633\u0644\u0627\u0645\u062a \u0631\u0627 \u0628\u0627 \u0686\u0627\u0644\u0634 \u062f\u0634\u0648\u0627\u0631 &#8220;\u0627\u0646\u062a\u062e\u0627\u0628 \u0622\u06af\u0627\u0647\u0627\u0646\u0647 \u0648 \u0639\u0627\u062f\u0644\u0627\u0646\u0647&#8221; \u0645\u0648\u0627\u062c\u0647 \u0633\u0627\u062e\u062a\u0647 \u0627\u0633\u062a. \u062f\u0631 \u0686\u0646\u06cc\u0646 \u0634\u0631\u0627\u06cc\u0637\u06cc\u060c\u00a0<strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a<\/strong> <strong>(Health Technology Assessment \u2013 HTA)<\/strong>\u00a0\u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u0627\u0628\u0632\u0627\u0631 \u0633\u06cc\u0627\u0633\u062a\u06cc \u0628\u06cc\u200c\u0628\u062f\u06cc\u0644 \u0628\u0631\u0627\u06cc \u0627\u0631\u0632\u0634\u200c\u06af\u0630\u0627\u0631\u06cc \u0639\u0644\u0645\u06cc\u060c \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0648 \u0627\u062e\u0644\u0627\u0642\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u062f\u0642\u06cc\u0642\u060c \u0646\u0642\u0634\u06cc \u0645\u062d\u0648\u0631\u06cc \u0627\u06cc\u0641\u0627 \u0645\u06cc\u200c\u06a9\u0646\u062f.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a \u0627\u06cc\u0631\u0627\u0646 \u0628\u0627 \u0645\u062d\u062f\u0648\u062f\u06cc\u062a \u0645\u0646\u0627\u0628\u0639\u060c \u062a\u0646\u0648\u0639 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0648\u0638\u0647\u0648\u0631 \u0648 \u0646\u0628\u0648\u062f \u0633\u0627\u062e\u062a\u0627\u0631 \u0645\u0646\u0633\u062c\u0645 HTA \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647\u060c \u062f\u0631 \u0646\u0642\u0637\u0647 \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u062d\u0633\u0627\u0633\u06cc \u0642\u0631\u0627\u0631 \u062f\u0627\u0631\u062f. \u0627\u06cc\u0646 \u0645\u0642\u0627\u0644\u0647 \u0628\u0627 \u0628\u0647\u0631\u0647\u200c\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0645\u062a\u062f\u0648\u0644\u0648\u0698\u06cc\u200c\u0647\u0627\u06cc \u0645\u0637\u0627\u0644\u0639\u0647 \u062a\u0637\u0628\u06cc\u0642\u06cc\u060c \u0637\u0631\u0627\u062d\u06cc \u0627\u0644\u06af\u0648 \u0648 \u0645\u062f\u0644\u060c \u0622\u06cc\u0646\u062f\u0647\u200c\u067e\u0698\u0648\u0647\u06cc \u0648 \u062a\u062f\u0648\u06cc\u0646 \u0646\u0642\u0634\u0647 \u0631\u0627\u0647\u060c \u0686\u0627\u0631\u0686\u0648\u0628\u06cc \u062c\u0627\u0645\u0639 \u0628\u0631\u0627\u06cc \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0646\u0638\u0627\u0645 HTA \u0627\u062e\u062a\u0635\u0627\u0635\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646 \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc\u200c\u062f\u0647\u062f.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u067e\u0633 \u0627\u0632 \u0645\u0631\u0648\u0631 \u062a\u062c\u0627\u0631\u0628 \u067e\u06cc\u0634\u0631\u0648 (NICE \u00a0\u0627\u0646\u06af\u0644\u0633\u062a\u0627\u0646\u060c CADTH \u00a0\u06a9\u0627\u0646\u0627\u062f\u0627\u060c IQWiG \u00a0\u0622\u0644\u0645\u0627\u0646\u060c PBAC \u00a0\u0627\u0633\u062a\u0631\u0627\u0644\u06cc\u0627) \u0648 \u062a\u062d\u0644\u06cc\u0644 \u0648\u0636\u0639\u06cc\u062a \u0645\u0648\u062c\u0648\u062f \u0648 \u0634\u06a9\u0627\u0641\u200c\u0647\u0627\u06cc \u0646\u0647\u0627\u062f\u06cc\u060c \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0648 \u0641\u0646\u06cc \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646\u060c \u0686\u0627\u0631\u0686\u0648\u0628 \u067e\u06cc\u0634\u0646\u0647\u0627\u062f\u06cc \u0634\u0627\u0645\u0644: (\u06f1) \u0627\u06cc\u062c\u0627\u062f &#8220;\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc&#8221; \u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u0646\u0647\u0627\u062f \u0645\u0633\u062a\u0642\u0644 \u0641\u0646\u06cc\u060c (\u06f2) \u062a\u062f\u0648\u06cc\u0646 \u0622\u06cc\u06cc\u0646\u200c\u0646\u0627\u0645\u0647 \u0627\u0631\u0632\u0634\u200c\u06af\u0630\u0627\u0631\u06cc \u0648\u06cc\u0698\u0647 \u0628\u0631\u0627\u06cc \u062a\u0633\u062a\u200c\u0647\u0627\u06cc \u0698\u0646\u0648\u0645\u06cc \u0648 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0628\u0627 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 \u0634\u0627\u062e\u0635\u200c\u0647\u0627\u06cc \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u00a0(ICER\u060c QALY) \u0648 \u062a\u062d\u0644\u06cc\u0644 \u062a\u0623\u062b\u06cc\u0631 \u0628\u0648\u062f\u062c\u0647\u060c (\u06f3) \u0637\u0631\u0627\u062d\u06cc \u0641\u0631\u0622\u06cc\u0646\u062f &#8220;\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u067e\u0648\u06cc\u0627 \u0648 \u062a\u0637\u0628\u06cc\u0642\u06cc&#8221;<\/span><br \/>\n<span style=\"color: #000000;\">(Dynamic &amp; Adaptive HTA) \u00a0\u0628\u0631\u0627\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0648\u0638\u0647\u0648\u0631\u060c (\u06f4) \u067e\u06cc\u0648\u0646\u062f \u0646\u0638\u0627\u0645\u200c\u0645\u0646\u062f \u0646\u062a\u0627\u06cc\u062c HTA \u0628\u0627 \u062a\u0635\u0645\u06cc\u0645\u200c\u0647\u0627\u06cc \u062a\u0639\u0631\u0641\u0647\u200c\u06af\u0630\u0627\u0631\u06cc\u060c \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647 \u067e\u0627\u06cc\u0647 \u0648 \u062a\u06a9\u0645\u06cc\u0644\u06cc \u0648 (\u06f5) \u0628\u0631\u0646\u0627\u0645\u0647 \u062a\u0648\u0627\u0646\u0645\u0646\u062f\u0633\u0627\u0632\u06cc \u0646\u06cc\u0631\u0648\u06cc \u0627\u0646\u0633\u0627\u0646\u06cc \u0648 \u0632\u06cc\u0631\u0633\u0627\u062e\u062a \u062f\u0627\u062f\u0647 \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f. \u062f\u0631 \u067e\u0627\u06cc\u0627\u0646\u060c \u0646\u0642\u0634\u0647 \u0631\u0627\u0647 \u067e\u0646\u062c\u200c\u0633\u0627\u0644\u0647 \u0648 \u062a\u0648\u0635\u06cc\u0647\u200c\u0647\u0627\u06cc \u0633\u06cc\u0627\u0633\u062a\u06cc \u0645\u0634\u062e\u0635 \u0628\u0631\u0627\u06cc \u062a\u062d\u0642\u0642 \u0646\u0638\u0627\u0645 HTA \u0647\u0648\u0634\u0645\u0646\u062f\u060c \u0634\u0641\u0627\u0641 \u0648 \u0639\u0627\u062f\u0644\u0627\u0646\u0647 \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646 \u062a\u062f\u0648\u06cc\u0646 \u0634\u062f\u0647 \u0627\u0633\u062a.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0648\u0627\u0698\u06af\u0627\u0646 \u06a9\u0644\u06cc\u062f\u06cc:<\/strong>\u00a0\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a (HTA)\u060c \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647\u060c \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc\u060c \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u200c\u0627\u06cc\u060c \u062d\u06a9\u0645\u0631\u0627\u0646\u06cc \u0633\u0644\u0627\u0645\u062a\u060c \u0627\u06cc\u0631\u0627\u0646.<\/span><\/p>\n<h2 style=\"text-align: justify;\"><span style=\"font-size: 14pt; color: #000000;\"><strong>\u00a0<\/strong><strong>\u0641\u0635\u0644 \u0627\u0648\u0644: \u0645\u0642\u062f\u0645\u0647 <\/strong><strong>\u2013<\/strong><strong> \u0636\u0631\u0648\u0631\u062a \u0627\u0631\u0632\u0634\u200c\u06af\u0630\u0627\u0631\u06cc \u0639\u0644\u0645\u06cc \u0648 \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u062f\u0631 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/h2>\n<h2><span style=\"font-size: 12pt; color: #000000;\"><strong>\u06f1-\u06f1)<\/strong> <strong>\u0627\u0646\u0641\u062c\u0627\u0631 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u062f\u0642\u06cc\u0642 \u0648 \u0686\u0627\u0644\u0634 \u0627\u0646\u062a\u062e\u0627\u0628<\/strong><\/span><\/h2>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u062f\u0631 \u062f\u0648 \u062f\u0647\u0647 \u0627\u062e\u06cc\u0631\u060c \u062a\u0639\u062f\u0627\u062f \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0648 \u0622\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u0647\u0645\u0631\u0627\u0647 \u062a\u0634\u062e\u06cc\u0635 (Companion Diagnostics) \u0631\u0634\u062f \u062a\u0635\u0627\u0639\u062f\u06cc \u06cc\u0627\u0641\u062a\u0647 \u0627\u0633\u062a. \u0633\u0627\u0632\u0645\u0627\u0646 \u063a\u0630\u0627 \u0648 \u062f\u0627\u0631\u0648\u06cc \u0622\u0645\u0631\u06cc\u06a9\u0627 (FDA) \u062a\u0627 \u0633\u0627\u0644 \u06f2\u06f0\u06f2\u06f5 \u0628\u06cc\u0634 \u0627\u0632 \u06f3\u06f5\u06f0 \u062f\u0627\u0631\u0648\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u0631\u0627 \u062a\u0623\u06cc\u06cc\u062f \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a \u0648 \u0647\u0632\u06cc\u0646\u0647 \u0647\u0631 \u062a\u0648\u0627\u0644\u06cc\u200c\u06cc\u0627\u0628\u06cc \u06a9\u0627\u0645\u0644 \u0698\u0646\u0648\u0645 (WGS) \u0627\u0632 \u0628\u06cc\u0634 \u0627\u0632 \u06f1\u06f0\u06f0 \u0645\u06cc\u0644\u06cc\u0648\u0646 \u062f\u0644\u0627\u0631 \u062f\u0631 \u0633\u0627\u0644 \u06f2\u06f0\u06f0\u06f1 \u0628\u0647 \u0632\u06cc\u0631 \u06f6\u06f0\u06f0 \u062f\u0644\u0627\u0631 \u062f\u0631 \u0633\u0627\u0644 \u06f2\u06f0\u06f2\u06f5 \u06a9\u0627\u0647\u0634 \u06cc\u0627\u0641\u062a\u0647 \u0627\u0633\u062a. \u0627\u06cc\u0646 \u0627\u0646\u0642\u0644\u0627\u0628 \u0641\u0646\u0627\u0648\u0631\u0627\u0646\u0647\u060c \u0627\u0645\u06cc\u062f\u0647\u0627\u06cc \u0632\u06cc\u0627\u062f\u06cc \u0628\u0631\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0635\u0639\u0628\u200c\u0627\u0644\u0639\u0644\u0627\u062c\u060c \u0633\u0631\u0637\u0627\u0646 \u0648 \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0627\u062f\u0631 \u0627\u06cc\u062c\u0627\u062f \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0627\u0645\u0627 \u0647\u0645\u06cc\u0646 \u0645\u0648\u0641\u0642\u06cc\u062a\u060c \u0646\u0638\u0627\u0645\u200c\u0647\u0627\u06cc \u0633\u0644\u0627\u0645\u062a \u0631\u0627 \u0628\u0627 \u067e\u0627\u0631\u0627\u062f\u0648\u06a9\u0633\u06cc \u062f\u0634\u0648\u0627\u0631 \u0645\u0648\u0627\u062c\u0647 \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a:\u00a0<strong>\u0686\u06af\u0648\u0646\u0647 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0628\u06cc\u0646 \u0635\u062f\u0647\u0627 \u0641\u0646\u0627\u0648\u0631\u06cc \u0646\u0648\u0638\u0647\u0648\u0631 \u06a9\u0647 \u0647\u0645\u06af\u06cc \u0627\u062f\u0639\u0627\u06cc \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0648 \u0646\u0648\u0622\u0648\u0631\u06cc \u062f\u0627\u0631\u0646\u062f\u060c \u0628\u0647\u062a\u0631\u06cc\u0646\u200c\u0647\u0627 \u0631\u0627 \u0628\u0631\u0627\u06cc \u0633\u0631\u0645\u0627\u06cc\u0647\u200c\u06af\u0630\u0627\u0631\u06cc \u0639\u0645\u0648\u0645\u06cc \u0627\u0646\u062a\u062e\u0627\u0628 \u06a9\u0631\u062f\u061f<\/strong>\u00a0\u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0698\u0646 \u062f\u0631\u0645\u0627\u0646\u06cc (\u0645\u0627\u0646\u0646\u062f Zolgensma \u0628\u0631\u0627\u06cc \u0622\u062a\u0631\u0648\u0641\u06cc \u0639\u0636\u0644\u0627\u0646\u06cc \u0646\u062e\u0627\u0639\u06cc) \u0628\u0627 \u0647\u0632\u06cc\u0646\u0647 \u0628\u06cc\u0634 \u0627\u0632 \u06f2 \u0645\u06cc\u0644\u06cc\u0648\u0646 \u062f\u0644\u0627\u0631 \u0628\u0631\u0627\u06cc \u0647\u0631 \u0628\u06cc\u0645\u0627\u0631\u060c \u0639\u0645\u0644\u0627\u064b \u0628\u062f\u0648\u0646 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc\u060c \u0628\u0648\u062f\u062c\u0647 \u0647\u0631 \u0628\u06cc\u0645\u0647\u200c\u06af\u0631\u06cc \u0631\u0627 \u0645\u062e\u062a\u0644 \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f. \u062a\u0633\u062a\u200c\u0647\u0627\u06cc \u0698\u0646\u0648\u0645\u06cc \u0686\u0646\u062f\u0698\u0646\u06cc \u06a9\u0647 \u067e\u06cc\u0634\u200c\u0628\u06cc\u0646\u06cc \u062e\u0637\u0631 \u0633\u0631\u0637\u0627\u0646 \u0631\u0627 \u0646\u0648\u06cc\u062f \u0645\u06cc\u200c\u062f\u0647\u0646\u062f\u060c \u06af\u0627\u0647 \u0641\u0627\u0642\u062f \u0627\u0639\u062a\u0628\u0627\u0631 \u0628\u0627\u0644\u06cc\u0646\u06cc \u06a9\u0627\u0641\u06cc \u0647\u0633\u062a\u0646\u062f \u0648 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u0646\u062f \u0645\u0646\u062c\u0631 \u0628\u0647 \u0645\u062f\u0627\u062e\u0644\u0627\u062a \u063a\u06cc\u0631\u0636\u0631\u0648\u0631\u06cc \u0648 \u0622\u0633\u06cc\u0628\u200c\u0632\u0646\u0646\u062f\u0647 \u0634\u0648\u0646\u062f.<\/span><\/p>\n<h2><span style=\"font-size: 12pt; color: #000000;\"><strong>2-1)<\/strong> <strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a <\/strong><strong>\u00a0(HTA)<\/strong><strong>:<\/strong> <strong>\u0627\u0628\u0632\u0627\u0631 \u0633\u06cc\u0627\u0633\u062a\u06cc \u067e\u0627\u0633\u062e\u06af\u0648<\/strong><\/span><\/h2>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">HTA \u0641\u0631\u0622\u06cc\u0646\u062f\u06cc \u0633\u06cc\u0633\u062a\u0645\u0627\u062a\u06cc\u06a9\u060c \u0634\u0641\u0627\u0641 \u0648 \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u0627\u0633\u062a \u06a9\u0647 \u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc\u060c \u0627\u0642\u062a\u0635\u0627\u062f\u06cc\u060c \u0627\u062c\u062a\u0645\u0627\u0639\u06cc\u060c \u0627\u062e\u0644\u0627\u0642\u06cc \u0648 \u0633\u0627\u0632\u0645\u0627\u0646\u06cc \u06cc\u06a9 \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a \u0631\u0627 \u067e\u06cc\u0634 \u0627\u0632 \u0648\u0631\u0648\u062f \u0628\u0647 \u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a \u06cc\u0627 \u067e\u0633 \u0627\u0632 \u0622\u0646 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u06cc\u200c\u06a9\u0646\u062f. \u062f\u0631 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647\u060c HTA \u00a0\u0648\u0638\u0627\u06cc\u0641 \u0648\u06cc\u0698\u0647\u200c\u0627\u06cc \u062f\u0627\u0631\u062f:<\/span><\/p>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u0646\u0633\u0628\u06cc:<\/strong>\u0622\u06cc\u0627 \u062a\u0633\u062a\/\u062f\u0627\u0631\u0648\u06cc \u0634\u062e\u0635\u06cc\u200c\u0634\u062f\u0647 \u0646\u0633\u0628\u062a \u0628\u0647 \u0645\u0631\u0627\u0642\u0628\u062a \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u060c \u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u0628\u0647\u062a\u0631\u06cc \u062f\u0627\u0631\u062f\u061f<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc:<\/strong>\u0628\u0647 \u0627\u0632\u0627\u06cc \u0647\u0631 \u0648\u0627\u062d\u062f \u0628\u0647\u0628\u0648\u062f (\u0645\u062b\u0644\u0627\u064b \u0633\u0627\u0644 \u0632\u0646\u062f\u06af\u06cc \u0628\u0627 \u06a9\u06cc\u0641\u06cc\u062a \u00a0\u2013 QALY)\u060c \u0647\u0632\u06cc\u0646\u0647 \u0627\u0636\u0627\u0641\u06cc \u0686\u0642\u062f\u0631 \u0627\u0633\u062a\u061f<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u062a\u062d\u0644\u06cc\u0644 \u062a\u0623\u062b\u06cc\u0631 \u0628\u0648\u062f\u062c\u0647:<\/strong>\u0627\u06af\u0631 \u0627\u06cc\u0646 \u0641\u0646\u0627\u0648\u0631\u06cc \u062a\u062d\u062a \u067e\u0648\u0634\u0634 \u0647\u0645\u06af\u0627\u0646\u06cc \u0642\u0631\u0627\u0631 \u06af\u06cc\u0631\u062f\u060c \u0686\u0647 \u0647\u0632\u064a\u0646\u0647\u200c\u0627\u06cc \u0628\u0647 \u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a \u062a\u062d\u0645\u06cc\u0644 \u0645\u06cc\u200c\u0634\u0648\u062f\u061f<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0627\u062e\u0644\u0627\u0642\u06cc \u0648 \u0627\u062c\u062a\u0645\u0627\u0639\u06cc:<\/strong>\u0622\u06cc\u0627 \u062a\u0648\u0632\u06cc\u0639 \u062f\u0633\u062a\u0631\u0633\u06cc \u0639\u0627\u062f\u0644\u0627\u0646\u0647 \u0627\u0633\u062a\u061f \u0622\u06cc\u0627 \u062a\u0628\u0639\u06cc\u0636 \u0698\u0646\u062a\u06cc\u06a9\u06cc \u0627\u06cc\u062c\u0627\u062f \u0645\u06cc\u200c\u06a9\u0646\u062f\u061f<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u062a\u0648\u0635\u06cc\u0647 \u0628\u0647 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u200c\u0627\u06cc:<\/strong>\u0628\u0627 \u0686\u0647 \u0634\u0631\u0627\u06cc\u0637\u06cc (\u0645\u062d\u062f\u0648\u062f\u06cc\u062a \u062a\u062c\u0648\u06cc\u0632\u060c \u0645\u0631\u0627\u06a9\u0632 \u062e\u0627\u0635\u060c \u062b\u0628\u062a \u062f\u0631 \u067e\u0627\u06cc\u06af\u0627\u0647 \u062f\u0627\u062f\u0647) \u067e\u0648\u0634\u0634 \u062f\u0627\u062f\u0647 \u0634\u0648\u062f\u061f<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u06a9\u0634\u0648\u0631\u0647\u0627\u06cc \u067e\u06cc\u0634\u0631\u0648 \u0645\u0627\u0646\u0646\u062f \u0627\u0646\u06af\u0644\u0633\u062a\u0627\u0646 (NICE)\u060c \u0622\u0644\u0645\u0627\u0646 \u00a0(IQWiG)\u060c \u06a9\u0627\u0646\u0627\u062f\u0627 (CADTH) \u0648 \u0627\u0633\u062a\u0631\u0627\u0644\u06cc\u0627 (PBAC) \u062f\u0647\u0647\u200c\u0647\u0627\u0633\u062a \u06a9\u0647 \u0627\u0632 HTA \u0628\u0631\u0627\u06cc \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u062f\u0631\u0628\u0627\u0631\u0647 \u067e\u0648\u0634\u0634 \u0647\u0645\u06af\u0627\u0646\u06cc \u062f\u0627\u0631\u0648\u0647\u0627 \u0648 \u062a\u0633\u062a\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u062f\u0642\u06cc\u0642 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f.<\/span><\/p>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u06f1-\u06f3<\/strong><strong>)<\/strong> <strong>\u0636\u0631\u0648\u0631\u062a \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0646\u0638\u0627\u0645<\/strong><strong> HTA <\/strong><strong>\u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a \u0627\u06cc\u0631\u0627\u0646 \u0628\u0627 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u0632\u06cc\u0631 \u0645\u0648\u0627\u062c\u0647 \u0627\u0633\u062a \u06a9\u0647 \u0636\u0631\u0648\u0631\u062a HTA \u0631\u0627 \u062f\u0648 \u0686\u0646\u062f\u0627\u0646 \u0645\u06cc\u200c\u06a9\u0646\u062f:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"color: #000000;\"><strong>\u0645\u0646\u0627\u0628\u0639 \u0645\u062d\u062f\u0648\u062f \u0648 \u0647\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u0631\u0648 \u0628\u0647 \u0631\u0634\u062f:<\/strong>\u0628\u0648\u062f\u062c\u0647 \u0633\u0627\u0632\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647\u200c\u06af\u0631 \u067e\u0627\u06cc\u0647 \u0633\u0627\u0644\u0627\u0646\u0647 \u0628\u0627 \u06a9\u0633\u0631\u06cc \u062c\u062f\u06cc \u0645\u0648\u0627\u062c\u0647 \u0627\u0633\u062a \u0648 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u06af\u0631\u0627\u0646\u200c\u0642\u06cc\u0645\u062a \u0634\u062e\u0635\u06cc\u200c\u0634\u062f\u0647 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u0646\u062f \u0628\u0647 \u0633\u0631\u0639\u062a \u0628\u0648\u062f\u062c\u0647 \u0631\u0627 \u0645\u0635\u0631\u0641 \u06a9\u0646\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0648\u0631\u0648\u062f \u0628\u06cc\u200c\u0646\u0638\u0645 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0648\u06cc\u0646:<\/strong>\u0634\u0631\u06a9\u062a\u200c\u0647\u0627\u06cc \u062f\u0627\u0646\u0634\u200c\u0628\u0646\u06cc\u0627\u0646 \u0648 \u0648\u0627\u0631\u062f\u06a9\u0646\u0646\u062f\u06af\u0627\u0646\u060c \u0627\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u0648 \u06a9\u06cc\u062a\u200c\u0647\u0627\u06cc \u0698\u0646\u062a\u06cc\u06a9 \u0645\u062a\u0639\u062f\u062f\u06cc \u0631\u0627 \u0628\u062f\u0648\u0646 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0628\u0647 \u0628\u0627\u0632\u0627\u0631 \u0639\u0631\u0636\u0647 \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0641\u0642\u062f\u0627\u0646 \u0646\u0638\u0627\u0645 \u0627\u0631\u0632\u0634\u200c\u06af\u0630\u0627\u0631\u06cc \u0634\u0641\u0627\u0641:<\/strong>\u062f\u0631 \u062d\u0627\u0644 \u062d\u0627\u0636\u0631\u060c \u062a\u0639\u0631\u0641\u0647 \u0622\u0632\u0645\u0627\u06cc\u0634\u200c\u0647\u0627\u06cc \u0698\u0646\u062a\u06cc\u06a9 \u0648 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0639\u0645\u062f\u062a\u0627\u064b \u0628\u0647 \u0635\u0648\u0631\u062a \u0645\u0648\u0631\u062f\u06cc \u0648 \u0628\u062f\u0648\u0646 \u0686\u0627\u0631\u0686\u0648\u0628 HTA \u062a\u0639\u06cc\u06cc\u0646 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u062e\u0637\u0631 \u0634\u06a9\u0627\u0641 \u0639\u062f\u0627\u0644\u062a:<\/strong>\u062f\u0631 \u0646\u0628\u0648\u062f \u00a0HTA\u060c \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0631\u0647\u0632\u06cc\u0646\u0647 \u0641\u0642\u0637 \u062f\u0631 \u062f\u0633\u062a\u0631\u0633 \u0627\u0642\u0644\u06cc\u062a \u0645\u0631\u0641\u0647 \u0642\u0631\u0627\u0631 \u06af\u06cc\u0631\u062f \u0648 \u0646\u0638\u0627\u0645 \u0628\u06cc\u0645\u0647 \u0646\u06cc\u0632 \u0646\u062a\u0648\u0627\u0646\u062f \u067e\u0648\u0634\u0634 \u0639\u0627\u062f\u0644\u0627\u0646\u0647 \u0641\u0631\u0627\u0647\u0645 \u06a9\u0646\u062f.<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0627\u06cc\u0646 \u0645\u0642\u0627\u0644\u0647\u060c \u0628\u0627 \u0631\u0648\u06cc\u06a9\u0631\u062f \u062d\u0627\u06a9\u0645\u06cc\u062a\u06cc \u0648 \u0628\u0627 \u0628\u0647\u0631\u0647\u200c\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0645\u062a\u062f\u0648\u0644\u0648\u0698\u06cc\u200c\u0647\u0627\u06cc \u062c\u0627\u0645\u0639\u0647 \u0627\u0646\u062f\u06cc\u0634\u06a9\u062f\u0647\u200c\u0647\u0627\u060c \u0686\u0627\u0631\u0686\u0648\u0628 \u062c\u0627\u0645\u0639\u06cc \u0628\u0631\u0627\u06cc \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0646\u0638\u0627\u0645 HTA \u0627\u062e\u062a\u0635\u0627\u0635\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646 \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc\u200c\u062f\u0647\u062f.<\/span><\/p>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u06f1-\u06f4<\/strong><strong>)<\/strong> <strong>\u0645\u062a\u062f\u0648\u0644\u0648\u0698\u06cc \u067e\u0698\u0648\u0647\u0634<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0628\u0631 \u0627\u0633\u0627\u0633 \u0645\u062a\u062f\u0648\u0644\u0648\u0698\u06cc\u200c\u0647\u0627\u06cc \u0627\u0635\u0644\u06cc \u0632\u06cc\u0631 \u0627\u06cc\u0646 \u067e\u0698\u0648\u0647\u0634 \u0645\u0631\u0627\u062d\u0644 \u0632\u06cc\u0631 \u0631\u0627 \u0637\u06cc \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a:<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u06f1)\u00a0<strong>\u0645\u0637\u0627\u0644\u0639\u0647 \u062a\u0637\u0628\u06cc\u0642\u06cc<\/strong>\u00a0\u062a\u062c\u0627\u0631\u0628 HTA \u062f\u0631 \u06f5 \u06a9\u0634\u0648\u0631\/\u0645\u0646\u0637\u0642\u0647 \u067e\u06cc\u0634\u0631\u0648 (\u0628\u0631\u06cc\u062a\u0627\u0646\u06cc\u0627\u060c \u06a9\u0627\u0646\u0627\u062f\u0627\u060c \u0622\u0644\u0645\u0627\u0646\u060c \u0627\u0633\u062a\u0631\u0627\u0644\u06cc\u0627 \u0648 \u0633\u0646\u06af\u0627\u067e\u0648\u0631) \u0628\u0627 \u062a\u0645\u0631\u06a9\u0632 \u0628\u0631 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc.<\/span><br \/>\n<span style=\"color: #000000;\">\u06f2)\u00a0<strong>\u062a\u062d\u0644\u06cc\u0644 \u0648\u0636\u0639\u06cc\u062a \u0645\u0648\u062c\u0648\u062f<\/strong>\u00a0\u062f\u0631 \u0627\u06cc\u0631\u0627\u0646: \u0638\u0631\u0641\u06cc\u062a\u200c\u0647\u0627\u06cc HTA\u060c \u0646\u0647\u0627\u062f\u0647\u0627\u06cc \u0630\u06cc\u200c\u0631\u0628\u0637\u060c \u0634\u06a9\u0627\u0641\u200c\u0647\u0627\u06cc \u0642\u0627\u0646\u0648\u0646\u06cc \u0648 \u0646\u0647\u0627\u062f\u06cc.<\/span><br \/>\n<span style=\"color: #000000;\">\u06f3)\u00a0<strong>\u0637\u0631\u0627\u062d\u06cc \u0627\u0644\u06af\u0648\u06cc \u0628\u0648\u0645\u06cc<\/strong>\u00a0\u0628\u0627 \u062f\u0631 \u0646\u0638\u0631 \u06af\u0631\u0641\u062a\u0646 \u0634\u0631\u0627\u06cc\u0637 \u0627\u0642\u062a\u0635\u0627\u062f\u06cc\u060c \u0641\u0646\u06cc \u0648 \u0641\u0631\u0647\u0646\u06af\u06cc \u0627\u06cc\u0631\u0627\u0646.<\/span><br \/>\n<span style=\"color: #000000;\">\u06f4)\u00a0<strong>\u0622\u06cc\u0646\u062f\u0647\u200c\u067e\u0698\u0648\u0647\u06cc<\/strong>\u00a0\u0633\u0646\u0627\u0631\u06cc\u0648\u0647\u0627\u06cc \u0645\u062d\u062a\u0645\u0644 (\u0633\u0647 \u0633\u0646\u0627\u0631\u06cc\u0648\u06cc \u062e\u0648\u0634\u200c\u0628\u06cc\u0646\u0627\u0646\u0647\u060c \u0645\u06cc\u0627\u0646\u06cc \u0648 \u0628\u062f\u0628\u06cc\u0646\u0627\u0646\u0647).<\/span><br \/>\n<span style=\"color: #000000;\">\u06f5)\u00a0<strong>\u062a\u062f\u0648\u06cc\u0646 \u0646\u0642\u0634\u0647 \u0631\u0627\u0647<\/strong>\u00a0\u0627\u062c\u0631\u0627\u06cc\u06cc \u067e\u0646\u062c\u200c\u0633\u0627\u0644\u0647.<\/span><\/p>\n<h2><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u062f\u0648\u0645: \u0645\u0628\u0627\u0646\u06cc \u0646\u0638\u0631\u06cc \u0648 \u062a\u062c\u0627\u0631\u0628 \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc<\/strong><strong> HTA <\/strong><strong>\u062f\u0631 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/h2>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u06f2-\u06f1<\/strong><strong>)<\/strong> <strong>\u0645\u0641\u0627\u0647\u06cc\u0645 \u06a9\u0644\u06cc\u062f\u06cc \u0648 \u0634\u0627\u062e\u0635\u200c\u0647\u0627\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc<\/strong><\/span><\/h3>\n<p><span style=\"color: #000000;\">\u067e\u06cc\u0634 \u0627\u0632 \u0628\u0631\u0631\u0633\u06cc \u062a\u0637\u0628\u06cc\u0642\u06cc\u060c \u062a\u0639\u0631\u06cc\u0641 \u0634\u0627\u062e\u0635\u200c\u0647\u0627\u06cc \u0627\u0635\u0644\u06cc \u0636\u0631\u0648\u0631\u06cc \u0627\u0633\u062a:<\/span><\/p>\n<table style=\"width: 94.9741%;\">\n<tbody>\n<tr>\n<td style=\"width: 32.9032%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\"><strong>\u0634\u0627\u062e\u0635<\/strong><\/span><\/td>\n<td style=\"width: 32.7419%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\"><strong>\u062a\u0639\u0631\u06cc\u0641<\/strong><\/span><\/td>\n<td style=\"width: 58.2799%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\"><strong>\u06a9\u0627\u0631\u0628\u0631\u062f \u062f\u0631 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 32.9032%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\"><strong>QALY<\/strong>\u00a0(Quality-Adjusted Life Year)<\/span><\/td>\n<td style=\"width: 32.7419%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">\u06cc\u06a9 \u0633\u0627\u0644 \u0632\u0646\u062f\u06af\u06cc \u0628\u0627 \u06a9\u06cc\u0641\u06cc\u062a \u06a9\u0627\u0645\u0644 \u0633\u0644\u0627\u0645\u062a = \u06f1 QALY. \u0645\u0631\u06af = \u06f0 QALY. \u00a0\u0628\u06cc\u0645\u0627\u0631\u06cc \u0645\u0632\u0645\u0646 \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u06f0\/\u06f5 QALY \u062f\u0631 \u0633\u0627\u0644 \u062f\u0627\u0634\u062a\u0647 \u0628\u0627\u0634\u062f.<\/span><\/td>\n<td style=\"width: 58.2799%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">\u0645\u0642\u0627\u06cc\u0633\u0647 \u0627\u0631\u0632\u0634 \u062f\u0631\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0634\u062e\u0635\u06cc\u200c\u0634\u062f\u0647 \u0628\u0627 \u062f\u0631\u0645\u0627\u0646 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 32.9032%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\"><strong>ICER<\/strong>\u00a0(Incremental Cost-Effectiveness Ratio)<\/span><\/td>\n<td style=\"width: 32.7419%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">(\u0647\u0632\u06cc\u0646\u0647 \u062f\u0631\u0645\u0627\u0646 \u062c\u062f\u06cc\u062f \u2013 \u0647\u0632\u06cc\u0646\u0647 \u062f\u0631\u0645\u0627\u0646 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f) \u00f7 (\u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u062c\u062f\u06cc\u062f \u2013 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f) = \u0647\u0632\u06cc\u0646\u0647 \u0628\u0647 \u0627\u0632\u0627\u06cc \u0647\u0631 QALY \u0627\u0636\u0627\u0641\u06cc<\/span><\/td>\n<td style=\"width: 58.2799%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">\u062a\u0639\u06cc\u06cc\u0646 \u0622\u0633\u062a\u0627\u0646\u0647 \u0645\u0642\u0631\u0648\u0646\u200c\u0628\u0647\u200c\u0635\u0631\u0641\u06af\u06cc (\u0645\u0639\u0645\u0648\u0644\u0627\u064b \u06f1 \u062a\u0627 \u06f3 \u0628\u0631\u0627\u0628\u0631 \u062a\u0648\u0644\u06cc\u062f \u0646\u0627\u062e\u0627\u0644\u0635 \u062f\u0627\u062e\u0644\u06cc \u0633\u0631\u0627\u0646\u0647)<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 32.9032%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\"><strong>BIA<\/strong>\u00a0(Budget Impact Analysis)<\/span><\/td>\n<td style=\"width: 32.7419%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">\u0628\u0631\u0622\u0648\u0631\u062f \u0647\u0632\u06cc\u0646\u0647 \u06a9\u0644 \u067e\u0630\u06cc\u0631\u0634 \u0641\u0646\u0627\u0648\u0631\u06cc \u062f\u0631 \u06cc\u06a9 \u0627\u0641\u0642 \u0632\u0645\u0627\u0646\u06cc \u0645\u0634\u062e\u0635 (\u0645\u062b\u0644\u0627\u064b \u06f3 \u06cc\u0627 \u06f5 \u0633\u0627\u0644)<\/span><\/td>\n<td style=\"width: 58.2799%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">\u067e\u06cc\u0634\u200c\u0628\u06cc\u0646\u06cc \u0641\u0634\u0627\u0631 \u0645\u0627\u0644\u06cc \u0628\u0631 \u0628\u06cc\u0645\u0647\u200c\u0647\u0627<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 32.9032%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\"><strong>HTA Core Model<\/strong><\/span><\/td>\n<td style=\"width: 32.7419%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">\u0686\u0627\u0631\u0686\u0648\u0628 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u06f9 \u062d\u0648\u0632\u0647\u200c\u0627\u06cc (\u0627\u0632 \u0633\u0644\u0627\u0645\u062a \u062a\u0627 \u0627\u062e\u0644\u0627\u0642 \u0648 \u0633\u0627\u0632\u0645\u0627\u0646\u06cc)<\/span><\/td>\n<td style=\"width: 58.2799%; text-align: center;\" width=\"200\"><span style=\"color: #000000;\">\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062c\u0627\u0645\u0639 \u0622\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u0698\u0646\u0648\u0645\u06cc<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"color: #000000;\"><strong>\u0646\u06a9\u062a\u0647 \u0648\u06cc\u0698\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc:<\/strong>\u00a0\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u062f\u0631 \u0627\u06cc\u0646\u062c\u0627 \u067e\u06cc\u0686\u06cc\u062f\u0647\u200c\u062a\u0631 \u0627\u0633\u062a \u0632\u06cc\u0631\u0627:<\/span><\/p>\n<ul>\n<li><span style=\"color: #000000;\">\u0622\u0632\u0645\u0627\u06cc\u0634 \u062a\u0634\u062e\u06cc\u0635\u06cc \u0648 \u062f\u0631\u0645\u0627\u0646 \u0647\u062f\u0641\u0645\u0646\u062f \u0627\u063a\u0644\u0628 \u0628\u0647 \u0635\u0648\u0631\u062a \u062c\u0641\u062a \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u06cc\u200c\u0634\u0648\u0646\u062f (\u0622\u0632\u0645\u0627\u06cc\u0634 \u0647\u0645\u0631\u0627\u0647 \u062f\u0631\u0645\u0627\u0646).<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u062f\u0631\u0645\u0627\u0646 \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0641\u0642\u0637 \u062f\u0631 \u0632\u06cc\u0631\u06af\u0631\u0648\u0647 \u0645\u0634\u062e\u0635\u06cc \u0627\u0632 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 (\u0622\u0646\u0647\u0627\u06cc\u06cc \u06a9\u0647 \u0628\u06cc\u0648\u0645\u0627\u0631\u06a9\u0631 \u0645\u062b\u0628\u062a \u062f\u0627\u0631\u0646\u062f) \u062f\u06cc\u062f\u0647 \u0634\u0648\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0647\u0632\u06cc\u0646\u0647 \u0622\u0632\u0645\u0627\u06cc\u0634 \u0628\u0627\u06cc\u062f \u062f\u0631 \u0645\u062f\u0644 \u0644\u062d\u0627\u0638 \u0634\u0648\u062f.<\/span><\/li>\n<\/ul>\n<h3><span style=\"color: #000000;\"><strong>\u06f2-\u06f2<\/strong><strong>)<\/strong> <strong>\u0645\u0637\u0627\u0644\u0639\u0647 \u062a\u0637\u0628\u06cc\u0642\u06cc: \u0686\u0647\u0627\u0631 \u0627\u0644\u06af\u0648\u06cc \u0628\u0631\u062a\u0631 \u062c\u0647\u0627\u0646\u06cc<\/strong><\/span><\/h3>\n<h4><span style=\"color: #000000;\"><strong>\u06f2-\u06f2-\u06f1<\/strong><strong>)<\/strong> <strong>\u0627\u0646\u06af\u0644\u0633\u062a\u0627\u0646<\/strong><strong> \u2013 <\/strong><strong>NICE<\/strong> <strong>(\u0645\u0624\u0633\u0633\u0647 \u0645\u0644\u06cc \u062a\u0639\u0627\u0644\u06cc \u0633\u0644\u0627\u0645\u062a \u0648 \u0645\u0631\u0627\u0642\u0628\u062a)<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">NICE \u0642\u062f\u06cc\u0645\u06cc\u200c\u062a\u0631\u06cc\u0646 \u0648 \u062a\u0623\u062b\u06cc\u0631\u06af\u0630\u0627\u0631\u062a\u0631\u06cc\u0646 \u0646\u0647\u0627\u062f HTA \u062c\u0647\u0627\u0646 (\u062a\u0623\u0633\u06cc\u0633 \u06f1\u06f9\u06f9\u06f9) \u0627\u0633\u062a. \u0633\u0627\u062e\u062a\u0627\u0631 \u0622\u0646 \u0634\u0627\u0645\u0644 \u06a9\u0645\u06cc\u062a\u0647\u200c\u0647\u0627\u06cc \u062a\u062e\u0635\u0635\u06cc (\u0645\u0627\u0646\u0646\u062f \u06a9\u0645\u06cc\u062a\u0647 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a) \u0648 \u0641\u0631\u0622\u06cc\u0646\u062f \u0634\u0641\u0627\u0641 \u062a\u06a9\u200c\u0645\u0631\u062d\u0644\u0647\u200c\u0627\u06cc \u0627\u0633\u062a.<\/span><\/p>\n<p><span style=\"color: #000000;\"><strong>\u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u06a9\u0644\u06cc\u062f\u06cc \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc:<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #000000;\">\u0627\u0646\u062a\u0634\u0627\u0631 \u0631\u0627\u0647\u0646\u0645\u0627\u0647\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635\u06cc (Diagnostics Guidance) \u0648\u06cc\u0698\u0647 \u0628\u0631\u0627\u06cc \u062a\u0633\u062a\u200c\u0647\u0627\u06cc \u0698\u0646\u0648\u0645\u06cc \u0648 \u0647\u0645\u0631\u0627\u0647 \u062f\u0631\u0645\u0627\u0646.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 \u0622\u0633\u062a\u0627\u0646\u0647 ICER \u0645\u0639\u0645\u0648\u0644\u0627\u064b \u0628\u06cc\u0646 \u00a3\u06f2\u06f0,\u06f0\u06f0\u06f0 \u062a\u0627 \u00a3\u06f3\u06f0,\u06f0\u06f0\u06f0 \u0628\u0647 \u0627\u0632\u0627\u06cc \u0647\u0631 QALY<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0628\u0631\u0646\u0627\u0645\u0647<strong>&#8220;<\/strong><strong>\u062a\u0623\u06cc\u06cc\u062f \u0628\u0627 \u067e\u0698\u0648\u0647\u0634 \u0628\u06cc\u0634\u062a\u0631<\/strong><strong>&#8220;<\/strong> <strong>(Evidence Development)<\/strong>\u00a0\u0628\u0631\u0627\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0628\u0627 \u0634\u0648\u0627\u0647\u062f \u0627\u0648\u0644\u06cc\u0647 \u0627\u0645\u06cc\u062f\u0648\u0627\u0631\u06a9\u0646\u0646\u062f\u0647 \u0627\u0645\u0627 \u0646\u0627\u06a9\u0627\u0641\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u0632 \u0633\u0627\u0644 \u06f2\u06f0\u06f2\u06f2\u060c \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc\u200c\u0647\u0627\u06cc \u062a\u0633\u0631\u06cc\u0639\u200c\u0634\u062f\u0647 \u0628\u0631\u0627\u06cc \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0634\u062e\u0635\u06cc\u200c\u0634\u062f\u0647 \u0633\u0631\u0637\u0627\u0646 (\u0628\u0627\u0632\u0628\u06cc\u0646\u06cc \u062f\u0631 \u06f9\u06f0 \u0631\u0648\u0632).<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0646\u0642\u0627\u0637 \u0642\u0648\u062a \u0642\u0627\u0628\u0644 \u0627\u0642\u062a\u0628\u0627\u0633:<\/strong>\u00a0\u0634\u0641\u0627\u0641\u06cc\u062a\u060c \u0645\u0634\u0627\u0631\u06a9\u062a \u0630\u06cc\u200c\u0646\u0641\u0639\u0627\u0646\u060c \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 \u0645\u062f\u0644\u200c\u0647\u0627\u06cc \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u060c \u067e\u06cc\u0648\u0646\u062f \u0645\u0633\u062a\u0642\u06cc\u0645 \u0628\u0627 \u062a\u0635\u0645\u06cc\u0645 \u067e\u0648\u0634\u0634 NHS.<\/span><\/p>\n<h4><span style=\"color: #000000;\"><strong>\u06f2-\u06f2-\u06f2<\/strong><strong>)<\/strong> <strong>\u06a9\u0627\u0646\u0627\u062f\u0627<\/strong><strong> \u2013 <\/strong><strong>CADTH<\/strong> <strong>(\u0622\u0698\u0627\u0646\u0633 \u062f\u0627\u0631\u0648\u0647\u0627 \u0648 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0633\u0644\u0627\u0645\u062a)<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">CADTH \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc\u200c\u0647\u0627\u06cc HTA \u0631\u0627 \u0628\u0631\u0627\u06cc \u0646\u0638\u0627\u0645\u200c\u0647\u0627\u06cc \u0627\u0633\u062a\u0627\u0646\u06cc \u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u062f\u0647\u062f. \u0648\u06cc\u0698\u06af\u06cc \u0628\u0631\u062c\u0633\u062a\u0647 \u0622\u0646\u00a0<strong>&#8220;<\/strong><strong>\u0628\u0631\u0646\u0627\u0645\u0647 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0633\u0631\u0637\u0627\u0646<\/strong><strong>&#8220;<\/strong> <strong>\u00a0<\/strong><strong>(pCODR)<\/strong> \u0627\u0633\u062a \u06a9\u0647 \u0627\u0632 \u0633\u0627\u0644 \u06f2\u06f0\u06f1\u06f1 \u062a\u0645\u0627\u0645 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0633\u0631\u0637\u0627\u0646 \u0631\u0627 \u0627\u0632 \u0646\u0638\u0631 \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0648 \u062a\u0623\u062b\u06cc\u0631 \u0628\u0648\u062f\u062c\u0647 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u06cc\u200c\u06a9\u0646\u062f.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0646\u0642\u0627\u0637 \u0642\u0648\u062a:<\/strong>\u00a0\u0645\u0634\u0627\u0631\u06a9\u062a \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0648 \u067e\u0632\u0634\u06a9\u0627\u0646 \u062f\u0631 \u0641\u0631\u0622\u06cc\u0646\u062f\u060c \u062a\u062d\u0644\u06cc\u0644 \u062a\u0623\u062b\u06cc\u0631 \u0628\u0648\u062f\u062c\u0647 \u0627\u0633\u062a\u0627\u0646\u06cc\u060c \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062a\u0637\u0628\u06cc\u0642\u06cc \u0628\u0627 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0645\u0648\u062c\u0648\u062f.<\/span><\/p>\n<h4><span style=\"color: #000000;\"><strong>\u06f2-\u06f2-\u06f3<\/strong><strong>)<\/strong> <strong>\u0622\u0644\u0645\u0627\u0646<\/strong><strong> \u2013 <\/strong><strong>IQWiG<\/strong> <strong>(\u0645\u0624\u0633\u0633\u0647 \u06a9\u06cc\u0641\u06cc\u062a \u0648 \u06a9\u0627\u0631\u0627\u06cc\u06cc \u062f\u0631 \u0645\u0631\u0627\u0642\u0628\u062a \u0633\u0644\u0627\u0645\u062a)<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">IQWiG \u062f\u0631 \u0633\u0627\u0644 \u06f2\u06f0\u06f0\u06f4 \u062a\u0623\u0633\u06cc\u0633 \u0634\u062f \u0648 \u0639\u0645\u062f\u062a\u0627\u064b \u0628\u0631\u00a0<strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u0632\u06cc\u062a \u0627\u0641\u0632\u0648\u062f\u0647<\/strong> <strong>(Added Benefit)<\/strong>\u00a0\u0645\u062a\u0645\u0631\u06a9\u0632 \u0627\u0633\u062a. \u0628\u0631 \u0627\u0633\u0627\u0633 \u0642\u0627\u0646\u0648\u0646 AMNOG \u00a0(\u06f2\u06f0\u06f1\u06f1)\u060c \u062a\u0648\u0644\u06cc\u062f\u06a9\u0646\u0646\u062f\u06af\u0627\u0646 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u062c\u062f\u06cc\u062f \u0628\u0627\u06cc\u062f \u062f\u0648\u0633\u06cc\u0647\u200c\u0627\u06cc \u0627\u0631\u0627\u0626\u0647 \u062f\u0647\u0646\u062f \u06a9\u0647 \u0645\u0632\u06cc\u062a \u062f\u0627\u0631\u0648\u06cc \u062c\u062f\u06cc\u062f \u0646\u0633\u0628\u062a \u0628\u0647 \u062f\u0631\u0645\u0627\u0646 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u0631\u0627 \u0627\u062b\u0628\u0627\u062a \u06a9\u0646\u062f.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0646\u0642\u0627\u0637 \u0642\u0648\u062a \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc:<\/strong>\u00a0\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u062e\u06cc\u0644\u06cc \u0633\u062e\u062a\u06af\u06cc\u0631\u0627\u0646\u0647 \u2013 \u062f\u0631 \u0635\u0648\u0631\u062a \u0639\u062f\u0645 \u0627\u062b\u0628\u0627\u062a \u0645\u0632\u06cc\u062a\u060c \u0642\u06cc\u0645\u062a \u062f\u0627\u0631\u0648 \u062f\u0631 \u0633\u0637\u062d \u062f\u0631\u0645\u0627\u0646 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u062a\u0639\u06cc\u06cc\u0646 \u0645\u06cc\u200c\u0634\u0648\u062f. \u0639\u062f\u0645 \u067e\u0630\u06cc\u0631\u0634 \u0634\u0648\u0627\u0647\u062f \u0636\u0639\u06cc\u0641.<\/span><\/p>\n<h4><span style=\"color: #000000;\"><strong>\u06f2-\u06f2-\u06f4<\/strong><strong>)<\/strong> <strong>\u0627\u0633\u062a\u0631\u0627\u0644\u06cc\u0627<\/strong><strong> \u2013 <\/strong><strong>PBAC<\/strong> <strong>(\u06a9\u0645\u06cc\u062a\u0647 \u0645\u0632\u0627\u06cc\u0627\u06cc \u062f\u0627\u0631\u0648\u06cc\u06cc)<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">PBAC \u00a0\u06cc\u06a9\u06cc \u0627\u0632 \u0642\u062f\u06cc\u0645\u06cc\u200c\u062a\u0631\u06cc\u0646 \u0646\u0647\u0627\u062f\u0647\u0627 (\u06f1\u06f9\u06f5\u06f3) \u0628\u0627 \u0633\u0627\u0628\u0642\u0647 \u0642\u0648\u06cc \u062f\u0631 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062f\u0627\u0631\u0648\u0647\u0627 \u0627\u0633\u062a. \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u060c \u0627\u0632 \u0645\u062f\u0644\u00a0<strong>&#8220;<\/strong><strong>\u062a\u062d\u0644\u06cc\u0644 \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0646\u0634\u0627\u0646\u0647<\/strong><strong>&#8220;<\/strong>\u00a0\u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f. \u0645\u0632\u06cc\u062a \u0648\u06cc\u0698\u0647: \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632\u00a0<strong>\u062a\u062d\u0644\u06cc\u0644 \u0628\u0648\u062f\u062c\u0647 \u062f\u0648\u0633\u0627\u0644\u0647 \u0648 \u067e\u0646\u062c\u200c\u0633\u0627\u0644\u0647<\/strong>\u00a0\u0642\u0648\u06cc \u0648 \u0645\u0630\u0627\u06a9\u0631\u0647 \u0642\u06cc\u0645\u062a \u0628\u0631 \u0627\u0633\u0627\u0633 ICER.<\/span><\/p>\n<h4><span style=\"color: #000000;\"><strong>\u06f2-\u06f2-\u06f5<\/strong><strong>)<\/strong> <strong>\u0633\u0646\u06af\u0627\u067e\u0648\u0631 <\/strong><strong>\u2013<\/strong><strong> \u0622\u0698\u0627\u0646\u0633 \u0639\u0644\u0648\u0645\u060c \u0641\u0646\u0627\u0648\u0631\u06cc \u0648 \u067e\u0698\u0648\u0647\u0634<\/strong> <strong>(A*STAR) <\/strong><strong>\u0648 \u0628\u0631\u0646\u0627\u0645\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0628\u0647 \u0639\u0646\u0648\u0627\u0646 \u0627\u0644\u06af\u0648\u06cc \u06a9\u0634\u0648\u0631 \u062f\u0631 \u062d\u0627\u0644 \u062a\u0648\u0633\u0639\u0647 \u067e\u06cc\u0634\u0631\u0641\u062a\u0647\u060c \u0633\u0646\u06af\u0627\u067e\u0648\u0631 \u0627\u0632 \u0631\u0648\u06cc\u06a9\u0631\u062f\u00a0<strong>&#8220;<\/strong><strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u0631\u062d\u0644\u0647\u200c\u0627\u06cc<\/strong><strong>&#8220;<\/strong>\u00a0\u0628\u0631\u0627\u06cc \u0622\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u0698\u0646\u0648\u0645\u06cc \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f: \u0633\u0637\u062d \u06cc\u06a9 (\u0634\u0648\u0627\u0647\u062f \u0642\u0648\u06cc) \u2192 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647 \u0639\u0645\u0648\u0645\u06cc. \u0633\u0637\u062d \u062f\u0648 (\u0634\u0648\u0627\u0647\u062f \u0645\u062a\u0648\u0633\u0637) \u2192 \u067e\u0648\u0634\u0634 \u0645\u062d\u062f\u0648\u062f \u062f\u0631 \u0645\u0631\u0627\u06a9\u0632 \u0645\u0646\u062a\u062e\u0628 + \u062c\u0645\u0639\u200c\u0622\u0648\u0631\u06cc \u062f\u0627\u062f\u0647. \u0633\u0637\u062d \u0633\u0647 (\u0634\u0648\u0627\u0647\u062f \u0636\u0639\u06cc\u0641) \u2192 \u0628\u062f\u0648\u0646 \u067e\u0648\u0634\u0634.<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u06f2-\u06f3<\/strong><strong>)<\/strong> <strong>\u062c\u0645\u0639\u200c\u0628\u0646\u062f\u06cc \u062a\u0637\u0628\u06cc\u0642\u06cc \u0648 \u062f\u0631\u0633\u200c\u0622\u0645\u0648\u062e\u062a\u0647\u200c\u0647\u0627<\/strong><\/span><\/h3>\n<table style=\"width: 95.3069%;\">\n<tbody>\n<tr>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\"><strong>\u06a9\u0634\u0648\u0631\/ \u0646\u0647\u0627\u062f<\/strong><\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\"><strong>\u0645\u062f\u0644 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc<\/strong><\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\"><strong>\u0622\u0633\u062a\u0627\u0646\u0647 \u00a0ICER<\/strong><\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\"><strong>\u062a\u0635\u0645\u06cc\u0645 \u067e\u0648\u0634\u0634<\/strong><\/span><\/td>\n<td style=\"width: 42.8571%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\"><strong>\u0648\u06cc\u0698\u06af\u06cc \u0648\u06cc\u0698\u0647 \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">NICE \u00a0(\u0627\u0646\u06af\u0644\u0633\u062a\u0627\u0646)<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0631\u0633\u0645\u06cc\u060c \u0634\u0641\u0627\u0641<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u00a3\u06f2\u06f0-\u06f3\u06f0k\/QALY<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0627\u0644\u0632\u0627\u0645\u200c\u0622\u0648\u0631 \u0628\u0631\u0627\u06cc NHS<\/span><\/td>\n<td style=\"width: 42.8571%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0631\u0627\u0647\u0646\u0645\u0627\u0647\u0627\u06cc \u062a\u0634\u062e\u06cc\u0635\u06cc \u062c\u062f\u0627\u06af\u0627\u0646\u0647<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">CADTH \u00a0(\u06a9\u0627\u0646\u0627\u062f\u0627)<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u063a\u06cc\u0631\u0627\u0644\u0632\u0627\u0645\u200c\u0622\u0648\u0631 \u0628\u0631\u0627\u06cc \u0627\u0633\u062a\u0627\u0646\u200c\u0647\u0627<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">$\u06f5\u06f0k CAD\/QALY<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u062a\u0648\u0635\u06cc\u0647\u200c\u0627\u06cc<\/span><\/td>\n<td style=\"width: 42.8571%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">pCODR \u00a0\u0648\u06cc\u0698\u0647 \u0633\u0631\u0637\u0627\u0646<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">IQWiG \u00a0(\u0622\u0644\u0645\u0627\u0646)<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0645\u0632\u06cc\u062a \u0627\u0641\u0632\u0648\u062f\u0647<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u063a\u06cc\u0631\u0631\u0633\u0645\u06cc (\u0645\u0630\u0627\u06a9\u0631\u0647)<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0642\u06cc\u0645\u062a\u200c\u06af\u0630\u0627\u0631\u06cc<\/span><\/td>\n<td style=\"width: 42.8571%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0627\u0644\u0632\u0627\u0645 \u0627\u062b\u0628\u0627\u062a \u0645\u0632\u06cc\u062a \u0646\u0633\u0628\u06cc<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">PBAC \u00a0(\u0627\u0633\u062a\u0631\u0627\u0644\u06cc\u0627)<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0631\u0633\u0645\u06cc\u060c \u062a\u0627\u0631\u06cc\u062e\u06cc<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">$\u06f4\u06f5k AUD\/QALY<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0627\u0644\u0632\u0627\u0645\u200c\u0622\u0648\u0631<\/span><\/td>\n<td style=\"width: 42.8571%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u062a\u062d\u0644\u06cc\u0644 \u0628\u0648\u062f\u062c\u0647 \u0642\u0648\u06cc<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0633\u0646\u06af\u0627\u067e\u0648\u0631<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0645\u0631\u062d\u0644\u0647\u200c\u0627\u06cc\u060c \u062a\u0637\u0628\u06cc\u0642\u06cc<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u0645\u062a\u0646\u0627\u0633\u0628 \u0628\u0627 GDP \u0633\u0631\u0627\u0646\u0647<\/span><\/td>\n<td style=\"width: 19.6232%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u062a\u062f\u0631\u06cc\u062c\u06cc<\/span><\/td>\n<td style=\"width: 42.8571%; text-align: center;\" width=\"120\"><span style=\"color: #000000;\">\u067e\u0648\u0634\u0634 \u0645\u062d\u062f\u0648\u062f+\u067e\u0698\u0648\u0647\u0634<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"color: #000000;\"><strong>\u062f\u0631\u0633\u200c\u0647\u0627\u06cc \u0627\u0635\u0644\u06cc \u0628\u0631\u0627\u06cc \u0627\u06cc\u0631\u0627\u0646:<\/strong><\/span><\/p>\n<p><span style=\"color: #000000;\">\u06f1) \u0627\u06cc\u062c\u0627\u062f \u0646\u0647\u0627\u062f \u0645\u0633\u062a\u0642\u0644 \u0641\u0646\u06cc \u0627\u0644\u0632\u0627\u0645\u06cc \u0627\u0633\u062a.<\/span><br \/>\n<span style=\"color: #000000;\">2) \u0634\u0641\u0627\u0641\u06cc\u062a \u0648 \u0645\u0634\u0627\u0631\u06a9\u062a \u0630\u06cc\u200c\u0646\u0641\u0639\u0627\u0646 (\u0628\u06cc\u0645\u0627\u0631\u0627\u0646\u060c \u067e\u0632\u0634\u06a9\u0627\u0646\u060c \u0628\u06cc\u0645\u0647\u200c\u0647\u0627) \u0627\u0639\u062a\u0628\u0627\u0631 \u062a\u0635\u0645\u06cc\u0645\u0627\u062a \u0631\u0627 \u0627\u0641\u0632\u0627\u06cc\u0634 \u0645\u06cc\u200c\u062f\u0647\u062f.<\/span><br \/>\n<span style=\"color: #000000;\">\u06f3) \u0622\u0633\u062a\u0627\u0646\u0647 ICER \u0628\u0627\u06cc\u062f \u0645\u062a\u0646\u0627\u0633\u0628 \u0628\u0627 \u062a\u0648\u0627\u0646 \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0627\u06cc\u0631\u0627\u0646 \u062a\u0639\u06cc\u06cc\u0646 \u0634\u0648\u062f.<\/span><br \/>\n<span style=\"color: #000000;\">\u06f4) \u0628\u0631\u0627\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0648\u0638\u0647\u0648\u0631\u060c \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u067e\u0648\u06cc\u0627 (\u0628\u0627 \u062c\u0645\u0639\u200c\u0622\u0648\u0631\u06cc \u062f\u0627\u062f\u0647 \u0648\u0627\u0642\u0639\u06cc) \u0636\u0631\u0648\u0631\u06cc \u0627\u0633\u062a.<\/span><br \/>\n<span style=\"color: #000000;\">\u06f5) \u067e\u06cc\u0648\u0646\u062f \u0646\u0638\u0627\u0645\u200c\u0645\u0646\u062f HTA \u0628\u0627 \u062a\u0639\u0631\u0641\u0647\u200c\u06af\u0630\u0627\u0631\u06cc \u0648 \u0628\u06cc\u0645\u0647 \u0627\u0644\u0632\u0627\u0645\u06cc \u0627\u0633\u062a.<\/span><\/p>\n<h2><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u0633\u0648\u0645: \u0648\u0636\u0639\u06cc\u062a \u0645\u0648\u062c\u0648\u062f<\/strong> <strong>HTA<\/strong> <strong>\u062f\u0631 \u0627\u06cc\u0631\u0627\u0646 <\/strong><strong>\u2013<\/strong><strong> \u0638\u0631\u0641\u06cc\u062a\u200c\u0647\u0627 \u0648 \u0634\u06a9\u0627\u0641\u200c\u0647\u0627<\/strong><\/span><\/h2>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u06f3-\u06f1<\/strong><strong>)<\/strong> <strong>\u062a\u0627\u0631\u06cc\u062e\u0686\u0647 \u0648 \u0633\u0627\u062e\u062a\u0627\u0631 \u0641\u0639\u0644\u06cc<\/strong> <strong>HTA<\/strong> <strong>\u062f\u0631 \u0627\u06cc\u0631\u0627\u0646<\/strong><\/span><\/h3>\n<p><span style=\"color: #000000;\">\u0627\u06cc\u0631\u0627\u0646 \u0627\u0632 \u0627\u0648\u0627\u06cc\u0644 \u062f\u0647\u0647 \u06f1\u06f3\u06f8\u06f0 \u0641\u0639\u0627\u0644\u06cc\u062a\u200c\u0647\u0627\u06cc \u067e\u0631\u0627\u06a9\u0646\u062f\u0647 HTA \u0631\u0627 \u0622\u063a\u0627\u0632 \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a. \u0645\u0647\u0645\u200c\u062a\u0631\u06cc\u0646 \u062f\u0633\u062a\u0627\u0648\u0631\u062f\u0647\u0627:<\/span><\/p>\n<ul>\n<li><span style=\"color: #000000;\"><strong>\u062f\u0641\u062a\u0631 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a<\/strong>\u062f\u0631 \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a (\u062a\u0623\u0633\u06cc\u0633 \u06f1\u06f3\u06f8\u06f6) \u2013 \u0627\u0645\u0627 \u0628\u0627 \u0646\u06cc\u0631\u0648\u06cc \u0627\u0646\u0633\u0627\u0646\u06cc \u0645\u062d\u062f\u0648\u062f (\u06a9\u0645\u062a\u0631 \u0627\u0632 \u06f1\u06f0 \u06a9\u0627\u0631\u0634\u0646\u0627\u0633 \u062a\u0645\u0627\u0645\u200c\u0648\u0642\u062a) \u0648 \u0628\u0648\u062f\u062c\u0647 \u0646\u0627\u0686\u06cc\u0632.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u06a9\u0645\u06cc\u062a\u0647 \u0645\u0644\u06cc<\/strong> <strong>HTA<\/strong>(\u06f1\u06f3\u06f9\u06f2) \u2013 \u0627\u0645\u0627 \u062c\u0644\u0633\u0627\u062a \u0622\u0646 \u0645\u0646\u0638\u0645 \u0646\u06cc\u0633\u062a \u0648 \u062e\u0631\u0648\u062c\u06cc\u200c\u0647\u0627\u06cc \u0622\u0646 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0647\u200c\u0647\u0627 \u0627\u0644\u0632\u0627\u0645\u200c\u0622\u0648\u0631 \u0646\u06cc\u0633\u062a.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0628\u0631\u062e\u06cc \u0645\u0637\u0627\u0644\u0639\u0627\u062a<\/strong> <strong>HTA<\/strong> <strong>\u067e\u0631\u0627\u06a9\u0646\u062f\u0647<\/strong>\u062f\u0631 \u062f\u0627\u0646\u0634\u06af\u0627\u0647\u200c\u0647\u0627\u06cc \u0639\u0644\u0648\u0645 \u067e\u0632\u0634\u06a9\u06cc (\u062a\u0647\u0631\u0627\u0646\u060c \u0627\u06cc\u0631\u0627\u0646\u060c \u0634\u0647\u06cc\u062f \u0628\u0647\u0634\u062a\u06cc) \u0639\u0645\u062f\u062a\u0627\u064b \u0628\u0647 \u0635\u0648\u0631\u062a \u067e\u0627\u06cc\u0627\u0646\u200c\u0646\u0627\u0645\u0647 \u0648 \u067e\u0698\u0648\u0647\u0634\u200c\u0647\u0627\u06cc \u0645\u0648\u0631\u062f\u06cc.<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #000000;\">\u0628\u0627 \u0627\u06cc\u0646 \u062d\u0627\u0644\u060c\u00a0<strong>\u0647\u06cc\u0686 \u0633\u0627\u062e\u062a\u0627\u0631 \u0627\u062e\u062a\u0635\u0627\u0635\u06cc \u0628\u0631\u0627\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong>\u00a0(\u0622\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u0698\u0646\u0648\u0645\u06cc\u060c \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f) \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f. \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u062f\u0631\u0628\u0627\u0631\u0647 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u200c\u0627\u06cc \u0627\u06cc\u0646 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627 \u0639\u0645\u062f\u062a\u0627\u064b \u0628\u0647 \u0635\u0648\u0631\u062a\u00a0<strong>\u0645\u0648\u0631\u062f\u06cc\u060c \u063a\u06cc\u0631\u0634\u0641\u0627\u0641 \u0648 \u0628\u062f\u0648\u0646 \u0634\u0648\u0627\u0647\u062f \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc<\/strong>\u00a0\u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/p>\n<h3><span style=\"color: #000000;\"><strong>\u06f3-\u06f2<\/strong><strong>)<\/strong> <strong>\u0634\u06a9\u0627\u0641\u200c\u0647\u0627\u06cc \u0627\u0635\u0644\u06cc \u062f\u0631 \u0646\u0638\u0627\u0645<\/strong><strong> HTA <\/strong><strong>\u0627\u06cc\u0631\u0627\u0646 \u0628\u0631\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/h3>\n<h4><span style=\"color: #000000;\"><strong>\u06f3-\u06f2-\u06f1<\/strong><strong>)<\/strong> <strong>\u0634\u06a9\u0627\u0641 \u0646\u0647\u0627\u062f\u06cc<\/strong><\/span><\/h4>\n<ul>\n<li><span style=\"color: #000000;\">\u0641\u0642\u062f\u0627\u0646 \u0646\u0647\u0627\u062f \u0645\u0633\u062a\u0642\u0644 \u0648 \u062a\u062e\u0635\u0635\u06cc \u0628\u0627 \u0627\u062e\u062a\u06cc\u0627\u0631 \u0627\u0644\u0632\u0627\u0645\u200c\u0622\u0648\u0631 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0647\u200c\u0647\u0627.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u067e\u0631\u0627\u06a9\u0646\u062f\u06af\u06cc \u0645\u0633\u0626\u0648\u0644\u06cc\u062a \u0628\u06cc\u0646 \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a (\u062f\u0641\u062a\u0631 HTA)\u060c \u0633\u0627\u0632\u0645\u0627\u0646 \u063a\u0630\u0627 \u0648 \u062f\u0627\u0631\u0648 \u0648 \u0633\u0627\u0632\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647\u200c\u06af\u0631.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0646\u0628\u0648\u062f \u0627\u0631\u062a\u0628\u0627\u0637 \u0646\u0638\u0627\u0645\u200c\u0645\u0646\u062f \u0628\u0627 \u0645\u0631\u0627\u06a9\u0632 \u062a\u0648\u0644\u06cc\u062f \u0634\u0648\u0627\u0647\u062f \u0628\u0627\u0644\u06cc\u0646\u06cc (\u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u060c \u067e\u0627\u06cc\u06af\u0627\u0647\u200c\u0647\u0627\u06cc \u062f\u0627\u062f\u0647).<\/span><\/li>\n<\/ul>\n<h4><span style=\"color: #000000;\"><strong>\u06f3-\u06f2-\u06f2<\/strong><strong>)<\/strong> <strong>\u0634\u06a9\u0627\u0641 \u0631\u0648\u0634\u200c\u0634\u0646\u0627\u062e\u062a\u06cc<\/strong><\/span><\/h4>\n<ul>\n<li><span style=\"color: #000000;\">\u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u0647\u0627\u06cc \u0628\u0648\u0645\u06cc \u0628\u0631\u0627\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0647\u0632\u06cc\u0646\u0647-\u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u062a\u0633\u062a\u200c\u0647\u0627\u06cc \u0698\u0646\u0648\u0645\u06cc \u062a\u062f\u0648\u06cc\u0646 \u0646\u0634\u062f\u0647 \u0627\u0633\u062a.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0641\u0642\u062f\u0627\u0646 \u0645\u062f\u0644\u200c\u0647\u0627\u06cc \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u062a\u0623\u06cc\u06cc\u062f\u0634\u062f\u0647 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0627\u062f\u0631 \u0648 \u0633\u0631\u0637\u0627\u0646 \u06a9\u0647 \u062d\u062c\u0645 \u0646\u0645\u0648\u0646\u0647 \u06a9\u0627\u0641\u06cc \u0646\u062f\u0627\u0631\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0639\u062f\u0645 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 \u0631\u0648\u0634\u200c\u0647\u0627\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u067e\u0648\u06cc\u0627 (\u0645\u0627\u0646\u0646\u062f &#8220;\u067e\u0648\u0634\u0634 \u0645\u0634\u0631\u0648\u0637 \u0628\u0627 \u062c\u0645\u0639\u200c\u0622\u0648\u0631\u06cc \u062f\u0627\u062f\u0647&#8221;).<\/span><\/li>\n<\/ul>\n<h4><span style=\"color: #000000;\"><strong>\u06f3-\u06f2-\u06f3<\/strong><strong>)<\/strong> <strong>\u0634\u06a9\u0627\u0641 \u062f\u0627\u062f\u0647 \u0648 \u0634\u0648\u0627\u0647\u062f<\/strong><\/span><\/h4>\n<ul>\n<li><span style=\"color: #000000;\">\u0646\u0628\u0648\u062f \u067e\u0627\u06cc\u06af\u0627\u0647 \u062f\u0627\u062f\u0647 \u0645\u0644\u06cc \u0647\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u0633\u0644\u0627\u0645\u062a (\u0642\u06cc\u0645\u062a \u062a\u0645\u0627\u0645 \u0634\u062f\u0647 \u062e\u062f\u0645\u0627\u062a \u0648 \u062f\u0627\u0631\u0648\u0647\u0627) \u0628\u0647 \u0635\u0648\u0631\u062a \u0642\u0627\u0628\u0644 \u062f\u0633\u062a\u0631\u0633\u06cc \u0628\u0631\u0627\u06cc \u062a\u062d\u0644\u06cc\u0644\u200c\u0647\u0627\u06cc HTA.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0641\u0642\u062f\u0627\u0646 \u062b\u0628\u062a \u0645\u0644\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0627\u062f\u0631 \u0648 \u0633\u0631\u0637\u0627\u0646 \u06a9\u0647 \u0627\u0645\u06a9\u0627\u0646 \u0628\u0631\u0622\u0648\u0631\u062f \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0648\u0627\u0642\u0639\u06cc \u0631\u0627 \u0641\u0631\u0627\u0647\u0645 \u06a9\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u062f\u0633\u062a\u0631\u0633\u06cc \u0645\u062d\u062f\u0648\u062f \u0628\u0647 \u062f\u0627\u062f\u0647\u200c\u0647\u0627\u06cc \u067e\u0631\u0648\u0646\u062f\u0647 \u0627\u0644\u06a9\u062a\u0631\u0648\u0646\u06cc\u06a9 \u0633\u0644\u0627\u0645\u062a \u0628\u0631\u0627\u06cc \u062a\u062d\u0644\u06cc\u0644\u200c\u0647\u0627\u06cc \u0637\u0648\u0644\u06cc.<\/span><\/li>\n<\/ul>\n<h4><span style=\"color: #000000;\"><strong>\u06f3-\u06f2-\u06f4<\/strong><strong>)<\/strong> <strong>\u0634\u06a9\u0627\u0641 \u0646\u06cc\u0631\u0648\u06cc \u0627\u0646\u0633\u0627\u0646\u06cc<\/strong><\/span><\/h4>\n<ul>\n<li><span style=\"color: #000000;\">\u062a\u0639\u062f\u0627\u062f \u0645\u062a\u062e\u0635\u0635\u0627\u0646 HTA \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646 \u06a9\u0645\u062a\u0631 \u0627\u0632 \u06f5\u06f0 \u0646\u0641\u0631 \u0627\u0633\u062a (\u062f\u0631 \u062d\u0627\u0644\u06cc \u06a9\u0647 \u0627\u0646\u06af\u0644\u0633\u062a\u0627\u0646 \u0628\u06cc\u0634 \u0627\u0632 \u06f3\u06f0\u06f0 \u0645\u062a\u062e\u0635\u0635 \u062a\u0645\u0627\u0645\u200c\u0648\u0642\u062a \u062f\u0627\u0631\u062f).<\/span><\/li>\n<li><span style=\"color: #000000;\">\u06a9\u0645\u0628\u0648\u062f \u0634\u062f\u06cc\u062f \u0627\u0642\u062a\u0635\u0627\u062f\u062f\u0627\u0646\u0627\u0646 \u0633\u0644\u0627\u0645\u062a \u0622\u0634\u0646\u0627 \u0628\u0627 \u0645\u062f\u0644\u200c\u0633\u0627\u0632\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0646\u0628\u0648\u062f \u0628\u0631\u0646\u0627\u0645\u0647 \u0622\u0645\u0648\u0632\u0634\u06cc \u0631\u0633\u0645\u06cc \u062a\u062e\u0635\u0635\u06cc HTA \u062f\u0631 \u0631\u0634\u062a\u0647\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc\u060c \u062f\u0627\u0631\u0648\u0633\u0627\u0632\u06cc \u0648 \u0628\u0647\u062f\u0627\u0634\u062a \u0639\u0645\u0648\u0645\u06cc.<\/span><\/li>\n<\/ul>\n<h4><span style=\"color: #000000;\"><strong>\u06f3-\u06f2-\u06f5<\/strong><strong>)<\/strong> <strong>\u0634\u06a9\u0627\u0641 \u0642\u0627\u0646\u0648\u0646\u06cc \u0648 \u062d\u0627\u06a9\u0645\u06cc\u062a\u06cc<\/strong><\/span><\/h4>\n<ul>\n<li><span style=\"color: #000000;\">\u0647\u06cc\u0686 \u0642\u0627\u0646\u0648\u0646\u06cc \u0627\u0644\u0632\u0627\u0645 \u0628\u0647 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc HTA \u0628\u0631\u0627\u06cc \u0648\u0631\u0648\u062f \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u062f\u0642\u06cc\u0642 \u0628\u0647 \u0646\u0638\u0627\u0645 \u0628\u06cc\u0645\u0647 \u0646\u062f\u0627\u0631\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0645\u0627\u062f\u0647 \u06f3\u06f9 \u0642\u0627\u0646\u0648\u0646 \u0628\u0631\u0646\u0627\u0645\u0647 \u0634\u0634\u0645 \u062a\u0648\u0633\u0639\u0647 (\u0627\u0631\u062a\u0642\u0627\u06cc HTA) \u0627\u062c\u0631\u0627\u06cc\u06cc \u0646\u0634\u062f\u0647 \u0627\u0633\u062a.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0622\u06cc\u06cc\u0646\u200c\u0646\u0627\u0645\u0647 \u062a\u0639\u0631\u0641\u0647\u200c\u06af\u0630\u0627\u0631\u06cc \u0622\u0632\u0645\u0627\u06cc\u0634\u200c\u0647\u0627\u06cc \u0698\u0646\u062a\u06cc\u06a9 \u0648 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 HTA \u0646\u06cc\u0633\u062a.<\/span><\/li>\n<\/ul>\n<h3><span style=\"color: #000000;\"><strong>\u06f3-\u06f3<\/strong><strong>)<\/strong> <strong>\u0639\u0648\u0627\u0642\u0628 \u0641\u0642\u062f\u0627\u0646<\/strong><strong> HTA <\/strong><strong>\u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646<\/strong><\/span><\/h3>\n<p><span style=\"color: #000000;\">\u062f\u0631 \u062d\u0627\u0644 \u062d\u0627\u0636\u0631\u060c \u0646\u0645\u0648\u0646\u0647\u200c\u0647\u0627\u06cc\u06cc \u0627\u0632 \u062a\u0635\u0645\u06cc\u0645\u0627\u062a \u063a\u06cc\u0631\u0634\u0641\u0627\u0641 \u0642\u0627\u0628\u0644 \u0645\u0634\u0627\u0647\u062f\u0647 \u0627\u0633\u062a:<\/span><\/p>\n<ul>\n<li><span style=\"color: #000000;\">\u0622\u0632\u0645\u0627\u06cc\u0634 NIPT (\u063a\u0631\u0628\u0627\u0644\u06af\u0631\u06cc \u0642\u0628\u0644 \u0627\u0632 \u062a\u0648\u0644\u062f) \u0628\u0627 \u0647\u0632\u06cc\u0646\u0647 4 \u062a\u0627 \u06f2\/\u06f5 \u0645\u06cc\u0644\u06cc\u0648\u0646 \u062a\u0648\u0645\u0627\u0646 \u0628\u0647 \u0635\u0648\u0631\u062a \u0622\u0632\u0627\u062f \u0639\u0631\u0636\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u0627\u0645\u0627 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u200c\u0627\u06cc \u0622\u0646 \u0645\u062d\u062f\u0648\u062f \u0648 \u0628\u062f\u0648\u0646 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u062f\u0631 \u062c\u0645\u0639\u06cc\u062a \u0627\u06cc\u0631\u0627\u0646 \u0627\u0633\u062a.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0633\u0631\u0637\u0627\u0646 (\u0645\u0627\u0646\u0646\u062f \u062a\u0631\u0627\u0633\u062a\u0648\u0632\u0648\u0645\u0627\u0628 \u0648 \u0627\u06cc\u0645\u0627\u062a\u06cc\u0646\u06cc\u0628) \u062a\u062d\u062a \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647 \u0642\u0631\u0627\u0631 \u062f\u0627\u0631\u0646\u062f\u060c \u0627\u0645\u0627 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc ICER \u0622\u0646\u200c\u0647\u0627 \u0646\u0633\u0628\u062a \u0628\u0647 \u06af\u0632\u06cc\u0646\u0647\u200c\u0647\u0627\u06cc \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646 (\u0645\u062b\u0644\u0627\u064b \u0628\u06cc\u0648\u0633\u06cc\u0645\u06cc\u0644\u0627\u0631\u0647\u0627) \u0627\u0646\u062c\u0627\u0645 \u0646\u0634\u062f\u0647 \u0627\u0633\u062a.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0622\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u0641\u0627\u0631\u0645\u0627\u06a9\u0648\u0698\u0646\u0648\u0645\u06cc\u06a9 \u0628\u0631\u0627\u06cc \u0648\u0627\u0631\u0641\u0627\u0631\u06cc\u0646 \u0648 \u06a9\u0644\u0648\u067e\u06cc\u062f\u0648\u06af\u0631\u0644 \u062f\u0631 \u0628\u0631\u062e\u06cc \u0645\u0631\u0627\u06a9\u0632 \u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u0627\u0645\u0627 \u0645\u0634\u062e\u0635 \u0646\u06cc\u0633\u062a \u0622\u06cc\u0627 \u0627\u0632 \u0646\u0638\u0631 \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0645\u0642\u0631\u0648\u0646\u200c\u0628\u0647\u200c\u0635\u0631\u0641\u0647 \u0647\u0633\u062a\u0646\u062f \u06cc\u0627 \u062e\u06cc\u0631.<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #000000;\">\u0627\u06cc\u0646 \u0648\u0636\u0639\u06cc\u062a \u0645\u0646\u062c\u0631 \u0628\u0647:\u00a0<strong>\u0627\u062a\u0644\u0627\u0641 \u0645\u0646\u0627\u0628\u0639 \u0645\u062d\u062f\u0648\u062f\u060c \u0646\u0627\u0628\u0631\u0627\u0628\u0631\u06cc \u062f\u0631 \u062f\u0633\u062a\u0631\u0633\u06cc\u060c \u0648 \u062a\u0636\u0639\u06cc\u0641 \u0627\u0639\u062a\u0645\u0627\u062f \u0628\u0647 \u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a<\/strong>\u00a0\u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/p>\n<h2><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u0686\u0647\u0627\u0631\u0645: \u0686\u0627\u0631\u0686\u0648\u0628 \u067e\u06cc\u0634\u0646\u0647\u0627\u062f\u06cc \u0646\u0638\u0627\u0645<\/strong><strong> HTA <\/strong><strong>\u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646<\/strong><\/span><\/h2>\n<p><span style=\"color: #000000;\">\u0628\u0631 \u0627\u0633\u0627\u0633 \u062a\u062d\u0644\u06cc\u0644 \u0634\u06a9\u0627\u0641\u200c\u0647\u0627 \u0648 \u062f\u0631\u0633\u200c\u0622\u0645\u0648\u062e\u062a\u0647\u200c\u0647\u0627\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc\u060c \u0686\u0627\u0631\u0686\u0648\u0628 \u0632\u06cc\u0631 \u0637\u0631\u0627\u062d\u06cc \u0634\u062f\u0647 \u0627\u0633\u062a.<\/span><\/p>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u06f4-\u06f1<\/strong><strong>)<\/strong> <strong>\u0627\u0631\u06a9\u0627\u0646 \u06a9\u0644\u06cc\u062f\u06cc \u0686\u0627\u0631\u0686\u0648\u0628<\/strong><\/span><\/h3>\n<h4><span style=\"color: #000000;\"><strong>\u0631\u06a9\u0646 \u0627\u0648\u0644: \u0627\u06cc\u062c\u0627\u062f <\/strong><strong>&#8220;<\/strong><strong>\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u0648 \u0641\u0631\u0627\u062f\u0642\u06cc\u0642<\/strong><strong>&#8220;<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u067e\u06cc\u0634\u0646\u0647\u0627\u062f \u062a\u0623\u0633\u06cc\u0633 \u0646\u0647\u0627\u062f\u06cc \u0645\u0633\u062a\u0642\u0644 \u0628\u0647 \u0646\u0627\u0645\u00a0<strong>&#8220;<\/strong><strong>\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u0627\u0631\u0632\u0634\u200c\u0622\u0641\u0631\u06cc\u0646\u06cc \u0648 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><strong>&#8220;<\/strong>\u00a0\u0628\u0627 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u0632\u06cc\u0631:<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"color: #000000;\"><strong>\u0627\u0633\u062a\u0642\u0644\u0627\u0644 \u0641\u0646\u06cc \u0648 \u0645\u0627\u0644\u06cc: <\/strong>\u0646\u0647 \u0632\u06cc\u0631\u0645\u062c\u0645\u0648\u0639\u0647 \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a \u0648 \u0646\u0647 \u0633\u0627\u0632\u0645\u0627\u0646 \u0628\u06cc\u0645\u0647\u060c \u0628\u0644\u06a9\u0647 \u0646\u0647\u0627\u062f\u06cc \u0639\u0645\u0648\u0645\u06cc \u063a\u06cc\u0631\u062f\u0648\u0644\u062a\u06cc \u0628\u0627 \u0647\u06cc\u0626\u062a \u0627\u0645\u0646\u0627\u06cc \u0645\u062a\u0634\u06a9\u0644 \u0627\u0632 \u0646\u0645\u0627\u06cc\u0646\u062f\u06af\u0627\u0646 \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a\u060c \u0633\u0627\u0632\u0645\u0627\u0646 \u0628\u0631\u0646\u0627\u0645\u0647 \u0648 \u0628\u0648\u062f\u062c\u0647\u060c \u0633\u0627\u0632\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647\u060c \u0646\u0638\u0627\u0645 \u067e\u0632\u0634\u06a9\u06cc\u060c \u062f\u0627\u0646\u0634\u06af\u0627\u0647\u200c\u0647\u0627 \u0648 \u0627\u0646\u062c\u0645\u0646\u200c\u0647\u0627\u06cc \u0639\u0644\u0645\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0628\u0648\u062f\u062c\u0647: <\/strong>\u0627\u0632 \u0645\u062d\u0644 \u06f0\/\u06f5\u066a \u0627\u0632 \u0645\u0646\u0627\u0628\u0639 \u0628\u06cc\u0645\u0647 \u0633\u0644\u0627\u0645\u062a (\u062a\u0642\u0631\u06cc\u0628\u0627\u064b \u06f1\u06f0\u06f0\u06f0 \u0645\u06cc\u0644\u06cc\u0627\u0631\u062f \u062a\u0648\u0645\u0627\u0646 \u062f\u0631 \u0633\u0627\u0644) \u0648 \u06a9\u0645\u06a9\u200c\u0647\u0627\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0648\u0638\u0627\u06cc\u0641 \u06a9\u0644\u06cc\u062f\u06cc:<\/strong><\/span>\n<ul>\n<li><span style=\"color: #000000;\">\u062a\u062f\u0648\u06cc\u0646 \u0648 \u0628\u0647\u200c\u0631\u0648\u0632\u0631\u0633\u0627\u0646\u06cc<strong>\u0631\u0627\u0647\u0646\u0645\u0627\u0647\u0627\u06cc \u0631\u0648\u0634\u200c\u0634\u0646\u0627\u062e\u062a\u06cc<\/strong>\u00a0\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0647\u0632\u06cc\u0646\u0647-\u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0628\u0631\u0627\u06cc \u0622\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u0698\u0646\u0648\u0645\u06cc\u060c \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0648 \u062f\u0631\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0698\u0646\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u0646\u062c\u0627\u0645 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc\u200c\u0647\u0627\u06cc HTA \u0628\u0647 \u062f\u0631\u062e\u0648\u0627\u0633\u062a \u0633\u0627\u0632\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647\u060c \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a \u06cc\u0627 \u062a\u0648\u0644\u06cc\u062f\u06a9\u0646\u0646\u062f\u06af\u0627\u0646.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u0646\u062a\u0634\u0627\u0631 \u06af\u0632\u0627\u0631\u0634\u200c\u0647\u0627\u06cc \u0639\u0645\u0648\u0645\u06cc \u0634\u0641\u0627\u0641 \u0648 \u062a\u0648\u0635\u06cc\u0647\u200c\u0647\u0627\u06cc \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u200c\u0627\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u06cc\u062c\u0627\u062f \u067e\u0627\u06cc\u06af\u0627\u0647 \u062f\u0627\u062f\u0647 \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc\u200c\u0634\u062f\u0647.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0647\u0645\u06a9\u0627\u0631\u06cc \u0628\u0627 \u0646\u0647\u0627\u062f\u0647\u0627\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc (NICE\u060c CADTH\u060c WHO).<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h4 style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0631\u06a9\u0646 \u062f\u0648\u0645: \u062a\u062f\u0648\u06cc\u0646 \u0622\u06cc\u06cc\u0646\u200c\u0646\u0627\u0645\u0647 \u0627\u0631\u0632\u0634\u200c\u06af\u0630\u0627\u0631\u06cc \u0648\u06cc\u0698\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0645\u0635\u0648\u0628\u0627\u062a \u0632\u06cc\u0631 \u0628\u0627\u06cc\u062f \u062a\u0648\u0633\u0637 \u0634\u0648\u0631\u0627\u06cc \u0639\u0627\u0644\u06cc \u0628\u06cc\u0645\u0647 \u0633\u0644\u0627\u0645\u062a \u0648 \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a \u062a\u0635\u0648\u06cc\u0628 \u0634\u0648\u062f:<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u06f1)\u00a0\u062a\u0639\u06cc\u06cc\u0646 \u0622\u0633\u062a\u0627\u0646\u0647<\/strong> <strong>ICER<\/strong> <strong>\u0628\u0648\u0645\u06cc:<\/strong>\u00a0\u067e\u06cc\u0634\u0646\u0647\u0627\u062f \u0645\u06cc\u200c\u0634\u0648\u062f \u0622\u0633\u062a\u0627\u0646\u0647 \u0645\u0642\u0631\u0648\u0646\u200c \u0628\u0647 \u200c\u0635\u0631\u0641\u06af\u06cc \u0628\u0631\u0627\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646 \u0645\u0639\u0627\u062f\u0644\u00a0<strong>\u06f1<\/strong> <strong>\u062a\u0627 <\/strong><strong>\u06f3<\/strong><strong> \u0628\u0631\u0627\u0628\u0631 \u062a\u0648\u0644\u06cc\u062f \u0646\u0627\u062e\u0627\u0644\u0635 \u062f\u0627\u062e\u0644\u06cc \u0633\u0631\u0627\u0646\u0647<\/strong>\u00a0(\u06a9\u0647 \u062f\u0631 \u0633\u0627\u0644 \u06f1\u06f4\u06f0\u06f4 \u062d\u062f\u0648\u062f \u06f5\u06f5\u06f0\u06f0 \u062f\u0644\u0627\u0631 \u0622\u0645\u0631\u06cc\u06a9\u0627 \u0627\u0633\u062a) \u06cc\u0639\u0646\u06cc \u06f5\u06f5\u06f0\u06f0 \u062a\u0627 \u06f1\u06f6\u06f5\u06f0\u06f0 \u062f\u0644\u0627\u0631 \u0628\u0647 \u0627\u0632\u0627\u06cc \u0647\u0631 QALY \u062a\u0639\u06cc\u06cc\u0646 \u0634\u0648\u062f. \u0628\u0631\u0627\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0645\u0631\u0628\u0648\u0637 \u0628\u0647 \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0627\u062f\u0631 \u0648 \u0628\u062f\u0648\u0646 \u062f\u0631\u0645\u0627\u0646 \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646\u060c \u0622\u0633\u062a\u0627\u0646\u0647 \u0628\u0627\u0644\u0627\u062a\u0631 (\u062a\u0627 \u06f5 \u0628\u0631\u0627\u0628\u0631) \u0642\u0627\u0628\u0644 \u0642\u0628\u0648\u0644 \u0627\u0633\u062a.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u06f2)<\/strong>\u00a0<strong>\u0627\u0644\u0632\u0627\u0645 \u0628\u0647 \u062a\u062d\u0644\u06cc\u0644 \u062a\u0623\u062b\u06cc\u0631 \u0628\u0648\u062f\u062c\u0647<\/strong><strong> (<\/strong><strong>BIA<\/strong><strong>) <\/strong><strong>\u0628\u0631\u0627\u06cc \u0647\u0631 \u0641\u0646\u0627\u0648\u0631\u06cc \u062c\u062f\u06cc\u062f:<\/strong>\u00a0\u0647\u0631 \u062a\u0648\u0635\u06cc\u0647 \u0628\u0647 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647 \u0628\u0627\u06cc\u062f \u0647\u0645\u0631\u0627\u0647 \u0628\u0627 \u0628\u0631\u0622\u0648\u0631\u062f \u0647\u0632\u06cc\u0646\u0647 \u0628\u0631 \u0628\u0648\u062f\u062c\u0647 \u0628\u06cc\u0645\u0647 \u062f\u0631 \u0627\u0641\u0642 \u06f3 \u0648 \u06f5 \u0633\u0627\u0644 \u0628\u0627\u0634\u062f.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u06f3)\u00a0\u0641\u0631\u0622\u06cc\u0646\u062f <\/strong><strong>&#8220;<\/strong><strong>\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u067e\u0648\u06cc\u0627 \u0648 \u062a\u0637\u0628\u06cc\u0642\u06cc<\/strong><strong>&#8220;<\/strong><strong> (Dynamic HTA)<\/strong><strong>:<\/strong>\u00a0\u0628\u0631\u0627\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0648\u0638\u0647\u0648\u0631 \u0628\u0627 \u0634\u0648\u0627\u0647\u062f \u0628\u0627\u0644\u06cc\u0646\u06cc \u0627\u0648\u0644\u06cc\u0647 \u0627\u0645\u0627 \u0627\u0645\u06cc\u062f\u0648\u0627\u0631\u06a9\u0646\u0646\u062f\u0647\u060c \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647 \u0645\u0634\u0631\u0648\u0637 (\u0645\u062b\u0644\u0627\u064b \u0628\u0631\u0627\u06cc \u06f2 \u0633\u0627\u0644) \u0647\u0645\u0631\u0627\u0647 \u0628\u0627 \u0627\u0644\u0632\u0627\u0645 \u0628\u0647 \u062c\u0645\u0639\u200c\u0622\u0648\u0631\u06cc \u062f\u0627\u062f\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0648 \u0647\u0632\u06cc\u0646\u0647 \u0648\u0627\u0642\u0639\u06cc \u062f\u0631 \u0633\u06cc\u0633\u062a\u0645 \u0633\u0644\u0627\u0645\u062a \u067e\u06cc\u0634\u0646\u0647\u0627\u062f \u0645\u06cc\u200c\u0634\u0648\u062f. \u067e\u0633 \u0627\u0632 \u06f2 \u0633\u0627\u0644\u060c \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u062c\u062f\u062f \u0648 \u062a\u0635\u0645\u06cc\u0645 \u0646\u0647\u0627\u06cc\u06cc.<\/span><\/p>\n<h4 style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0631\u06a9\u0646 \u0633\u0648\u0645: \u067e\u06cc\u0648\u0646\u062f \u0646\u0638\u0627\u0645\u200c\u0645\u0646\u062f<\/strong> <strong>HTA<\/strong> <strong>\u0628\u0627 \u062a\u0639\u0631\u0641\u0647\u200c\u06af\u0630\u0627\u0631\u06cc \u0648 \u0628\u06cc\u0645\u0647<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u062d\u0644\u0642\u0647 \u0627\u062a\u0635\u0627\u0644:<\/strong>\u00a0\u06a9\u0645\u06cc\u062a\u0647 \u0645\u0634\u062a\u0631\u06a9 HTA-\u0628\u06cc\u0645\u0647 \u0645\u062a\u0634\u06a9\u0644 \u0627\u0632 \u0646\u0645\u0627\u06cc\u0646\u062f\u06af\u0627\u0646 \u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u00a0HTA\u060c \u0633\u0627\u0632\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647 \u067e\u0627\u06cc\u0647 (\u0633\u0644\u0627\u0645\u062a\u060c \u062a\u0623\u0645\u06cc\u0646 \u0627\u062c\u062a\u0645\u0627\u0639\u06cc\u060c \u0631\u0648\u0633\u062a\u0627\u06cc\u06cc\u0627\u0646) \u0648 \u0633\u0627\u0632\u0645\u0627\u0646 \u063a\u0630\u0627 \u0648 \u062f\u0627\u0631\u0648.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0641\u0631\u0622\u06cc\u0646\u062f \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc:<\/strong><\/span><\/p>\n<ol style=\"text-align: justify;\">\n<li><span style=\"color: #000000;\">\u062a\u0648\u0644\u06cc\u062f\u06a9\u0646\u0646\u062f\u0647 \u06cc\u0627 \u062f\u0631\u062e\u0648\u0627\u0633\u062a\u200c\u06a9\u0646\u0646\u062f\u0647\u060c \u0641\u0631\u0645 \u0647\u0627\u06cc HTA \u0631\u0627 \u0628\u0647 \u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u0627\u0631\u0627\u0626\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f (\u0637\u0628\u0642 \u0631\u0627\u0647\u0646\u0645\u0627\u06cc \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f).<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0645\u0631\u06a9\u0632 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0627\u0648\u0644\u06cc\u0647 (\u062d\u062f\u0627\u06a9\u062b\u0631 \u06f6 \u0645\u0627\u0647) \u0648 \u06af\u0632\u0627\u0631\u0634 \u0639\u0645\u0648\u0645\u06cc \u0645\u0646\u062a\u0634\u0631 \u0645\u06cc\u200c\u06a9\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u06a9\u0645\u06cc\u062a\u0647 \u0645\u0634\u062a\u0631\u06a9 HTA-\u0628\u06cc\u0645\u0647\u060c \u0628\u0631 \u0627\u0633\u0627\u0633 \u06af\u0632\u0627\u0631\u0634\u060c \u062a\u0635\u0645\u06cc\u0645 \u0628\u0647<strong>\u0633\u0647 \u062d\u0627\u0644\u062a<\/strong>\u00a0\u0645\u06cc\u200c\u06af\u06cc\u0631\u062f:<\/span>\n<ul>\n<li><span style=\"color: #000000;\"><strong>\u067e\u0648\u0634\u0634 \u06a9\u0627\u0645\u0644<\/strong>(\u0628\u062f\u0648\u0646 \u0645\u062d\u062f\u0648\u062f\u06cc\u062a) \u2190 \u062f\u0631 \u0635\u0648\u0631\u062a\u06cc \u06a9\u0647 ICER \u06a9\u0645\u062a\u0631 \u0627\u0632 \u0622\u0633\u062a\u0627\u0646\u0647 \u06f1 \u0628\u0631\u0627\u0628\u0631 GDP \u0628\u0627\u0634\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u067e\u0648\u0634\u0634 \u0645\u0634\u0631\u0648\u0637<\/strong>(\u0628\u0627 \u0645\u062d\u062f\u0648\u062f\u06cc\u062a \u062a\u062c\u0648\u06cc\u0632\u060c \u0645\u0631\u0627\u06a9\u0632 \u062e\u0627\u0635\u060c \u06cc\u0627 \u0634\u0631\u0637 \u0645\u0634\u0627\u0631\u06a9\u062a \u062f\u0631 \u067e\u0698\u0648\u0647\u0634) \u2190 ICER \u0628\u06cc\u0646 \u06f1 \u062a\u0627 \u06f3 \u0628\u0631\u0627\u0628\u0631 GDP.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0628\u062f\u0648\u0646 \u067e\u0648\u0634\u0634<\/strong>(\u0628\u0627 \u0627\u0645\u06a9\u0627\u0646 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0622\u0632\u0627\u062f \u062a\u0648\u0633\u0637 \u0628\u06cc\u0645\u0627\u0631) \u2190 ICER \u0628\u06cc\u0634 \u0627\u0632 \u06f3 \u0628\u0631\u0627\u0628\u0631 GDP \u06cc\u0627 \u0641\u0642\u062f\u0627\u0646 \u0634\u0648\u0627\u0647\u062f \u0627\u062b\u0631\u0628\u062e\u0634\u06cc.<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"color: #000000;\">\u0633\u0627\u0632\u0645\u0627\u0646 \u063a\u0630\u0627 \u0648 \u062f\u0627\u0631\u0648 \u0628\u0627 \u0647\u0645\u06a9\u0627\u0631\u06cc \u0645\u0631\u06a9\u0632\u060c \u0642\u06cc\u0645\u062a \u062f\u0627\u0631\u0648\/ \u0622\u0632\u0645\u0627\u06cc\u0634 \u0631\u0627 \u0628\u0631 \u0627\u0633\u0627\u0633 ICER \u0648 BIA \u0645\u0630\u0627\u06a9\u0631\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f (\u0645\u062f\u0644 \u0642\u06cc\u0645\u062a\u200c\u06af\u0630\u0627\u0631\u06cc \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0627\u0631\u0632\u0634).<\/span><\/li>\n<\/ol>\n<h4 style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u0631\u06a9\u0646 \u0686\u0647\u0627\u0631\u0645: \u062a\u0648\u0627\u0646\u0645\u0646\u062f\u0633\u0627\u0632\u06cc \u0648 \u0638\u0631\u0641\u06cc\u062a\u200c\u0633\u0627\u0632\u06cc<\/strong><\/span><\/h4>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u06f1)\u00a0\u0628\u0631\u0646\u0627\u0645\u0647 \u0622\u0645\u0648\u0632\u0634 \u0646\u06cc\u0631\u0648\u06cc \u0627\u0646\u0633\u0627\u0646\u06cc:<\/strong>\u00a0\u0627\u06cc\u062c\u0627\u062f \u062f\u0648\u0631\u0647 \u06a9\u0627\u0631\u0634\u0646\u0627\u0633\u06cc \u0627\u0631\u0634\u062f \u0648 \u062f\u06a9\u062a\u0631\u06cc \u062a\u062e\u0635\u0635\u06cc \u00ab\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a \u0648 \u0627\u0642\u062a\u0635\u0627\u062f \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u00bb \u062f\u0631 \u062f\u0627\u0646\u0634\u06af\u0627\u0647\u200c\u0647\u0627\u06cc \u0628\u0631\u062a\u0631 \u0639\u0644\u0648\u0645 \u067e\u0632\u0634\u06a9\u06cc (\u062a\u0647\u0631\u0627\u0646\u060c \u0627\u06cc\u0631\u0627\u0646\u060c \u0634\u0647\u06cc\u062f \u0628\u0647\u0634\u062a\u06cc) \u0628\u0627 \u062d\u0645\u0627\u06cc\u062a \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a. \u0628\u0648\u0631\u0633\u200c\u0647\u0627\u06cc \u06a9\u0648\u062a\u0627\u0647\u200c\u0645\u062f\u062a \u0628\u0631\u0627\u06cc \u06a9\u0627\u0631\u0622\u0645\u0648\u0632\u06cc \u062f\u0631 NICE \u0648 \u00a0CADTH.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u06f2)\u00a0\u0632\u06cc\u0631\u0633\u0627\u062e\u062a \u062f\u0627\u062f\u0647:<\/strong>\u00a0\u0627\u06cc\u062c\u0627\u062f &#8220;\u067e\u0627\u06cc\u06af\u0627\u0647 \u0645\u0644\u06cc \u062f\u0627\u062f\u0647\u200c\u0647\u0627\u06cc \u0647\u0632\u06cc\u0646\u0647 \u0648 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0633\u0644\u0627\u0645\u062a&#8221; \u0628\u0627 \u062f\u0633\u062a\u0631\u0633\u06cc \u06a9\u0646\u062a\u0631\u0644\u200c\u0634\u062f\u0647 \u0628\u0631\u0627\u06cc \u062a\u062d\u0644\u06cc\u0644\u06af\u0631\u0627\u0646 HTA \u060c \u00a0\u06cc\u06a9\u067e\u0627\u0631\u0686\u0647\u200c\u0633\u0627\u0632\u06cc \u067e\u0631\u0648\u0646\u062f\u0647 \u0627\u0644\u06a9\u062a\u0631\u0648\u0646\u06cc\u06a9 \u0633\u0644\u0627\u0645\u062a \u0648 \u062f\u0627\u062f\u0647\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647 \u0628\u0631\u0627\u06cc \u0628\u0631\u0622\u0648\u0631\u062f \u0647\u0632\u06cc\u0646\u0647 \u0648\u0627\u0642\u0639\u06cc \u062f\u0631\u0645\u0627\u0646.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u06f3)\u00a0\u0647\u0645\u06a9\u0627\u0631\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc<\/strong><strong>:<\/strong>\u00a0\u0639\u0636\u0648\u06cc\u062a \u062f\u0631 \u0634\u0628\u06a9\u0647 \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc HTA (INAHTA) \u0648 \u0634\u0628\u06a9\u0647 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0634\u062e\u0635\u06cc\u200c\u0634\u062f\u0647 (PerMedHTA)\u060c \u00a0\u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 \u0627\u0628\u0632\u0627\u0631\u0647\u0627\u06cc \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u0645\u0627\u0646\u0646\u062f \u0645\u062f\u0644\u200c\u0647\u0627\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc NICE (DIAs) \u0628\u0627 \u067e\u0627\u0631\u0627\u0645\u062a\u0631\u0647\u0627\u06cc \u0628\u0648\u0645\u06cc\u200c\u0634\u062f\u0647.<\/span><\/p>\n<h4><span style=\"color: #000000;\"><strong>\u0631\u06a9\u0646 \u067e\u0646\u062c\u0645: \u0634\u0641\u0627\u0641\u06cc\u062a\u060c \u0645\u0634\u0627\u0631\u06a9\u062a \u0648 \u0639\u062f\u0627\u0644\u062a<\/strong><\/span><\/h4>\n<ul>\n<li><span style=\"color: #000000;\">\u0627\u0646\u062a\u0634\u0627\u0631 \u062a\u0645\u0627\u0645 \u06af\u0632\u0627\u0631\u0634\u200c\u0647\u0627\u06cc HTA (\u0628\u0647 \u062c\u0632 \u0627\u0637\u0644\u0627\u0639\u0627\u062a \u0645\u062d\u0631\u0645\u0627\u0646\u0647 \u062a\u062c\u0627\u0631\u06cc) \u062f\u0631 \u067e\u0627\u06cc\u06af\u0627\u0647 \u0639\u0645\u0648\u0645\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u062a\u0634\u06a9\u06cc\u0644<strong>\u06a9\u0645\u06cc\u062a\u0647 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0648 \u0639\u0645\u0648\u0645<\/strong>\u00a0\u062f\u0631 \u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u0628\u0631\u0627\u06cc \u0627\u0631\u0627\u0626\u0647 \u062f\u06cc\u062f\u06af\u0627\u0647\u200c\u0647\u0627\u06cc \u0627\u062c\u062a\u0645\u0627\u0639\u06cc \u0648 \u0627\u062e\u0644\u0627\u0642\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u062a\u0636\u0645\u06cc\u0646 \u0639\u062f\u0645 \u062a\u0628\u0639\u06cc\u0636: \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc\u06cc \u06a9\u0647 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0627\u062f\u0631 \u0648 \u06a9\u0648\u062f\u06a9\u0627\u0646 \u0647\u0633\u062a\u0646\u062f\u060c \u0628\u0627 \u0622\u0633\u062a\u0627\u0646\u0647\u200c\u0647\u0627\u06cc \u0627\u0646\u0639\u0637\u0627\u0641\u200c\u067e\u0630\u06cc\u0631\u062a\u0631 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0634\u0648\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u0644\u0632\u0627\u0645 \u0628\u0647 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062a\u0623\u062b\u06cc\u0631 \u0639\u062f\u0627\u0644\u062a: \u0647\u0631 \u06af\u0632\u0627\u0631\u0634 HTA \u0628\u0627\u06cc\u062f \u0634\u0627\u0645\u0644 \u0628\u062e\u0634\u06cc \u062f\u0631\u0628\u0627\u0631\u0647 \u062a\u0623\u062b\u06cc\u0631 \u0628\u0631 \u0646\u0627\u0628\u0631\u0627\u0628\u0631\u06cc\u200c\u0647\u0627\u06cc \u0633\u0644\u0627\u0645\u062a \u0628\u0627\u0634\u062f.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u067e\u0646\u062c\u0645: \u0646\u0642\u0634\u0647 \u0631\u0627\u0647 \u0627\u062c\u0631\u0627\u06cc\u06cc \u067e\u0646\u062c\u200c\u0633\u0627\u0644\u0647<\/strong><\/span><\/h2>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0645\u0631\u062d\u0644\u0647 \u0627\u0648\u0644: \u0628\u0646\u06cc\u0627\u0646\u200c\u06af\u0630\u0627\u0631\u06cc (\u0633\u0627\u0644 \u0627\u0648\u0644<\/strong><strong>)<\/strong><\/span><\/h3>\n<table style=\"width: 93.9314%;\">\n<tbody>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u0627\u0648\u0644\u0648\u06cc\u062a<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\"><strong>\u0641\u0639\u0627\u0644\u06cc\u062a<\/strong><\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\"><strong>\u0645\u062a\u0648\u0644\u06cc \u067e\u06cc\u0634\u0646\u0647\u0627\u062f\u06cc<\/strong><\/span><\/td>\n<td style=\"width: 40.8585%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\"><strong>\u062e\u0631\u0648\u062c\u06cc \u06a9\u0644\u06cc\u062f\u06cc<\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\">\u06f1<\/span><\/td>\n<td style=\"width: 45.469%;\" width=\"282\"><span style=\"color: #000000;\">\u062a\u0635\u0648\u06cc\u0628 &#8220;\u0622\u06cc\u06cc\u0646\u200c\u0646\u0627\u0645\u0647 \u062a\u0623\u0633\u06cc\u0633 \u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc&#8221; \u062f\u0631 \u0647\u06cc\u0626\u062a \u0648\u0632\u06cc\u0631\u0627\u0646<\/span><\/td>\n<td style=\"width: 27.663%;\" width=\"170\"><span style=\"color: #000000;\">\u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a + \u0633\u0627\u0632\u0645\u0627\u0646 \u0628\u0631\u0646\u0627\u0645\u0647<\/span><\/td>\n<td style=\"width: 40.8585%;\" width=\"104\"><span style=\"color: #000000;\">\u0645\u0635\u0648\u0628\u0647 \u0647\u06cc\u0626\u062a \u062f\u0648\u0644\u062a<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\">\u06f2<\/span><\/td>\n<td style=\"width: 45.469%;\" width=\"282\"><span style=\"color: #000000;\">\u062a\u0623\u0645\u06cc\u0646 \u0628\u0648\u062f\u062c\u0647 \u0627\u0648\u0644\u06cc\u0647 (\u06f1\u06f0\u06f0 \u0645\u06cc\u0644\u06cc\u0627\u0631\u062f \u062a\u0648\u0645\u0627\u0646) \u0628\u0631\u0627\u06cc \u0631\u0627\u0647\u200c\u0627\u0646\u062f\u0627\u0632\u06cc \u0645\u0631\u06a9\u0632<\/span><\/td>\n<td style=\"width: 27.663%;\" width=\"170\"><span style=\"color: #000000;\">\u0633\u0627\u0632\u0645\u0627\u0646 \u0628\u0631\u0646\u0627\u0645\u0647 + \u062e\u0632\u0627\u0646\u0647<\/span><\/td>\n<td style=\"width: 40.8585%;\" width=\"104\"><span style=\"color: #000000;\">\u0631\u062f\u06cc\u0641 \u0628\u0648\u062f\u062c\u0647<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\">\u06f3<\/span><\/td>\n<td style=\"width: 45.469%;\" width=\"282\"><span style=\"color: #000000;\">\u062a\u062f\u0648\u06cc\u0646 \u067e\u06cc\u0634\u200c\u0646\u0648\u06cc\u0633 &#8220;\u0631\u0627\u0647\u0646\u0645\u0627\u06cc \u0631\u0648\u0634\u200c\u0634\u0646\u0627\u062e\u062a\u06cc HTA \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc&#8221; \u0628\u0627 \u0645\u0634\u0627\u0631\u06a9\u062a \u062f\u0627\u0646\u0634\u06af\u0627\u0647\u06cc\u0627\u0646 \u0648 \u00a0NICE<\/span><\/td>\n<td style=\"width: 27.663%;\" width=\"170\"><span style=\"color: #000000;\">\u0645\u0631\u06a9\u0632 \u062f\u0631 \u062d\u0627\u0644 \u062a\u0623\u0633\u06cc\u0633 + \u0627\u0646\u062c\u0645\u0646 HTA \u00a0\u0627\u06cc\u0631\u0627\u0646<\/span><\/td>\n<td style=\"width: 40.8585%;\" width=\"104\"><span style=\"color: #000000;\">\u0633\u0646\u062f \u0631\u0627\u0647\u0646\u0645\u0627<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\">\u06f4<\/span><\/td>\n<td style=\"width: 45.469%;\" width=\"282\"><span style=\"color: #000000;\">\u0634\u0646\u0627\u0633\u0627\u06cc\u06cc \u0648 \u0627\u0648\u0644\u0648\u06cc\u062a\u200c\u0628\u0646\u062f\u06cc \u06f1\u06f0 \u0641\u0646\u0627\u0648\u0631\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u0628\u0631\u0627\u06cc \u0627\u0631\u0632\u06cc\u0627\u0632\u06cc \u0641\u0648\u0631\u06cc (\u0628\u0631 \u0627\u0633\u0627\u0633 \u0647\u0632\u06cc\u0646\u0647 \u0628\u0627\u0644\u0627 \u0648 \u062d\u062c\u0645 \u0627\u0633\u062a\u0641\u0627\u062f\u0647)<\/span><\/td>\n<td style=\"width: 27.663%;\" width=\"170\"><span style=\"color: #000000;\">\u0633\u0627\u0632\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647 + \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a<\/span><\/td>\n<td style=\"width: 40.8585%;\" width=\"104\">\n<p style=\"text-align: center;\"><span style=\"color: #000000;\">\u0641\u0647\u0631\u0633\u062a \u0627\u0648\u0644\u0648\u06cc\u062a<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0645\u0631\u062d\u0644\u0647 \u062f\u0648\u0645: \u062a\u0648\u0633\u0639\u0647 \u067e\u0627\u06cc\u0644\u0648\u062a (\u0633\u0627\u0644 \u062f\u0648\u0645 \u0648 \u0633\u0648\u0645<\/strong><strong>)<\/strong><\/span><\/h3>\n<table style=\"width: 93.569%;\">\n<tbody>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u0627\u0648\u0644\u0648\u06cc\u062a<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\"><strong>\u0641\u0639\u0627\u0644\u06cc\u062a<\/strong><\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\"><strong>\u0645\u062a\u0648\u0644\u06cc<\/strong><\/span><\/td>\n<td style=\"width: 40.3816%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\"><strong>\u062e\u0631\u0648\u062c\u06cc<\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f1<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u0627\u062c\u0631\u0627\u06cc \u067e\u0627\u06cc\u0644\u0648\u062a \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0628\u0631\u0627\u06cc \u06f5 \u0641\u0646\u0627\u0648\u0631\u06cc (\u0645\u062b\u0644\u0627\u064b \u0622\u0632\u0645\u0627\u06cc\u0634 NIPT\u060c \u062f\u0627\u0631\u0648\u06cc \u062a\u0631\u0627\u0633\u062a\u0648\u0632\u0648\u0645\u0627\u0628\u060c \u062a\u0633\u062a \u0641\u0627\u0631\u0645\u0627\u06a9\u0648\u0698\u0646\u0648\u0645\u06cc\u06a9 \u0648\u0627\u0631\u0641\u0627\u0631\u06cc\u0646\u060c \u0698\u0646 \u062f\u0631\u0645\u0627\u0646\u06cc SMA\u060c \u0622\u0632\u0645\u0627\u06cc\u0634 BRCA)<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc \u00a0HTA<\/span><\/td>\n<td style=\"width: 40.3816%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u06f5 \u06af\u0632\u0627\u0631\u0634 \u06a9\u0627\u0645\u0644 + \u062a\u0648\u0635\u06cc\u0647 \u067e\u0648\u0634\u0634<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f2<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u0637\u0631\u0627\u062d\u06cc \u0648 \u067e\u06cc\u0627\u062f\u0647\u200c\u0633\u0627\u0632\u06cc \u0633\u0627\u0645\u0627\u0646\u0647 \u062b\u0628\u062a \u0627\u0644\u06a9\u062a\u0631\u0648\u0646\u06cc\u06a9 \u00a0HTA \u0648 \u062a\u062d\u0644\u06cc\u0644 \u0628\u0648\u062f\u062c\u0647<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc + \u0633\u0627\u0632\u0645\u0627\u0646 \u0641\u0646\u0627\u0648\u0631\u06cc \u0627\u0637\u0644\u0627\u0639\u0627\u062a<\/span><\/td>\n<td style=\"width: 40.3816%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u0633\u0627\u0645\u0627\u0646\u0647 \u062a\u062d\u062a \u0648\u0628<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f3<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u0628\u0631\u06af\u0632\u0627\u0631\u06cc \u06f3 \u062f\u0648\u0631\u0647 \u0622\u0645\u0648\u0632\u0634\u06cc \u062a\u062e\u0635\u0635\u06cc HTA \u0628\u0631\u0627\u06cc \u06f1\u06f0\u06f0 \u06a9\u0627\u0631\u0634\u0646\u0627\u0633 \u0628\u06cc\u0645\u0647 \u0648 \u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u062f\u0627\u0646\u0634\u06af\u0627\u0647 \u0639\u0644\u0648\u0645 \u067e\u0632\u0634\u06a9\u06cc \u062a\u0647\u0631\u0627\u0646 + \u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc<\/span><\/td>\n<td style=\"width: 40.3816%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u06af\u0648\u0627\u0647\u06cc \u0622\u0645\u0648\u0632\u0634\u06cc<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f4<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u0627\u0646\u0639\u0642\u0627\u062f \u062a\u0641\u0627\u0647\u0645\u0646\u0627\u0645\u0647 \u0628\u0627 NICE \u0648 CADTH \u0628\u0631\u0627\u06cc \u0627\u0646\u062a\u0642\u0627\u0644 \u062f\u0627\u0646\u0634 \u0648 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f\u0647\u0627<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u0648\u0632\u0627\u0631\u062a \u0628\u0647\u062f\u0627\u0634\u062a + \u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc<\/span><\/td>\n<td style=\"width: 40.3816%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u0645\u0648\u0627\u0641\u0642\u062a\u0646\u0627\u0645\u0647 \u0647\u0645\u06a9\u0627\u0631\u06cc<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0645\u0631\u062d\u0644\u0647 \u0633\u0648\u0645: \u0645\u0642\u06cc\u0627\u0633\u200c\u067e\u0630\u06cc\u0631\u06cc \u0648 \u0646\u0647\u0627\u062f\u06cc\u0646\u0647\u200c\u0633\u0627\u0632\u06cc (\u0633\u0627\u0644 \u0686\u0647\u0627\u0631\u0645 \u0648 \u067e\u0646\u062c\u0645<\/strong><strong>)<\/strong><\/span><\/h3>\n<table style=\"width: 94.6545%;\">\n<tbody>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u0627\u0648\u0644\u0648\u06cc\u062a<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\"><strong>\u0641\u0639\u0627\u0644\u06cc\u062a<\/strong><\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\"><strong>\u0645\u062a\u0648\u0644\u06cc<\/strong><\/span><\/td>\n<td style=\"width: 41.8124%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\"><strong>\u062e\u0631\u0648\u062c\u06cc<\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f1<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u0627\u0644\u0632\u0627\u0645 \u062a\u0645\u0627\u0645\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u062c\u062f\u06cc\u062f \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u0628\u0647 \u0627\u062e\u0630 \u062a\u0623\u06cc\u06cc\u062f HTA \u067e\u06cc\u0634 \u0627\u0632 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647 (\u0627\u0632 \u0637\u0631\u06cc\u0642 \u0627\u0635\u0644\u0627\u062d \u0642\u0627\u0646\u0648\u0646)<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u0645\u062c\u0644\u0633 + \u0634\u0648\u0631\u0627\u06cc \u0639\u0627\u0644\u06cc \u0628\u06cc\u0645\u0647<\/span><\/td>\n<td style=\"width: 41.8124%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u0642\u0627\u0646\u0648\u0646 \u0627\u0635\u0644\u0627\u062d\u06cc<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f2<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u06af\u0633\u062a\u0631\u0634 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc\u200c\u0647\u0627 \u0628\u0647 \u06f5\u06f0 \u0641\u0646\u0627\u0648\u0631\u06cc \u0627\u0648\u0644\u0648\u06cc\u062a\u200c\u062f\u0627\u0631 \u0637\u06cc \u0633\u0627\u0644<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc<\/span><\/td>\n<td style=\"width: 41.8124%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u067e\u0627\u06cc\u06af\u0627\u0647 \u062f\u0627\u062f\u0647 \u0645\u0644\u06cc<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f3<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u0627\u06cc\u062c\u0627\u062f &#8220;\u0635\u0646\u062f\u0648\u0642 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0648\u0638\u0647\u0648\u0631&#8221; \u0628\u0631\u0627\u06cc \u067e\u0648\u0634\u0634 \u0645\u0634\u0631\u0648\u0637 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0628\u0633\u06cc\u0627\u0631 \u06af\u0631\u0627\u0646 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0627\u062f\u0631 \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 HTA \u00a0\u067e\u0648\u06cc\u0627<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u0633\u0627\u0632\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0628\u06cc\u0645\u0647 + \u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc<\/span><\/td>\n<td style=\"width: 41.8124%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u0635\u0646\u062f\u0648\u0642 \u0639\u0645\u0644\u06cc\u0627\u062a\u06cc<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 7.79014%; text-align: center;\" width=\"45\"><span style=\"color: #000000;\"><strong>\u06f4<\/strong><\/span><\/td>\n<td style=\"width: 45.469%; text-align: center;\" width=\"282\"><span style=\"color: #000000;\">\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062a\u0623\u062b\u06cc\u0631 \u0646\u0638\u0627\u0645 HTA \u0628\u0631 \u0628\u0648\u062f\u062c\u0647 \u0628\u06cc\u0645\u0647 \u0648 \u0639\u062f\u0627\u0644\u062a \u0633\u0644\u0627\u0645\u062a (\u06af\u0632\u0627\u0631\u0634 \u0633\u0627\u0644\u0627\u0646\u0647 \u0628\u0647 \u0645\u062c\u0644\u0633)<\/span><\/td>\n<td style=\"width: 27.663%; text-align: center;\" width=\"170\"><span style=\"color: #000000;\">\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc + \u0645\u0631\u06a9\u0632 \u067e\u0698\u0648\u0647\u0634\u200c\u0647\u0627\u06cc \u0645\u062c\u0644\u0633<\/span><\/td>\n<td style=\"width: 41.8124%; text-align: center;\" width=\"104\"><span style=\"color: #000000;\">\u06af\u0632\u0627\u0631\u0634 \u0634\u0641\u0627\u0641\u06cc\u062a<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u0634\u0634\u0645: \u0633\u0646\u0627\u0631\u06cc\u0648\u0647\u0627\u06cc \u0622\u06cc\u0646\u062f\u0647<\/strong><strong> \u2013 <\/strong><strong>\u0633\u0647 \u0645\u0633\u06cc\u0631 \u0645\u062d\u062a\u0645\u0644 \u0628\u0631\u0627\u06cc<\/strong><strong> HTA <\/strong><strong>\u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u062f\u0631 \u0627\u06cc\u0631\u0627\u0646<\/strong><\/span><\/h2>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0628\u0627 \u0628\u0647\u0631\u0647\u200c\u06af\u06cc\u0631\u06cc \u0627\u0632 \u0622\u06cc\u0646\u062f\u0647\u200c\u067e\u0698\u0648\u0647\u06cc\u060c \u0633\u0647 \u0633\u0646\u0627\u0631\u06cc\u0648\u06cc \u0627\u0635\u0644\u06cc \u062a\u062f\u0648\u06cc\u0646 \u0634\u062f\u0647 \u0627\u0633\u062a:<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0633\u0646\u0627\u0631\u06cc\u0648\u06cc <\/strong><strong>\u06f1: <\/strong><strong>&#8220;<\/strong><strong>\u062a\u062d\u0648\u0644 \u0647\u0648\u0634\u0645\u0646\u062f<\/strong><strong>&#8220;<\/strong><strong> (\u0645\u0637\u0644\u0648\u0628)<\/strong><\/span><\/h3>\n<ul style=\"text-align: justify;\">\n<li><span style=\"color: #000000;\">\u062a\u0635\u0648\u06cc\u0628 \u0648 \u0627\u062c\u0631\u0627\u06cc \u06a9\u0627\u0645\u0644 \u0686\u0627\u0631\u0686\u0648\u0628 \u067e\u06cc\u0634\u0646\u0647\u0627\u062f\u06cc.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0645\u0631\u06a9\u0632 \u0645\u0644\u06cc HTA \u0628\u0627 \u0628\u0648\u062f\u062c\u0647 \u06a9\u0627\u0641\u06cc \u0648 \u0627\u0633\u062a\u0642\u0644\u0627\u0644 \u0639\u0645\u0644 \u0627\u06cc\u062c\u0627\u062f \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u06a9\u0644\u06cc\u0647 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u0642\u0628\u0644 \u0627\u0632 \u067e\u0648\u0634\u0634 \u0628\u06cc\u0645\u0647\u060c \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0647\u0632\u06cc\u0646\u0647 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0645\u06cc\u200c\u0634\u0648\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">ICER \u0628\u0648\u0645\u06cc \u0648 \u0622\u0633\u062a\u0627\u0646\u0647 \u0634\u0641\u0627\u0641 \u062a\u0639\u0631\u06cc\u0641 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0646\u0638\u0627\u0645 \u0628\u06cc\u0645\u0647 \u0627\u0632 \u0645\u0646\u0627\u0628\u0639 \u0630\u062e\u06cc\u0631\u0647\u200c\u0634\u062f\u0647 (\u0628\u0627 \u062d\u0630\u0641 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u06a9\u0645\u200c\u0627\u0631\u0632\u0634) \u0628\u0631\u0627\u06cc \u067e\u0648\u0634\u0634 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0628\u0627 \u0627\u0631\u0632\u0634 \u0628\u0627\u0644\u0627 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0646\u062a\u06cc\u062c\u0647:<\/strong>\u0627\u0641\u0632\u0627\u06cc\u0634 \u06a9\u0627\u0631\u0627\u06cc\u06cc\u060c \u0639\u062f\u0627\u0644\u062a \u062f\u0631 \u062f\u0633\u062a\u0631\u0633\u06cc\u060c \u0648 \u0631\u0634\u062f \u0627\u0642\u062a\u0635\u0627\u062f \u062f\u0627\u0646\u0634\u200c\u0628\u0646\u06cc\u0627\u0646 \u0633\u0644\u0627\u0645\u062a.<\/span><\/li>\n<\/ul>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0633\u0646\u0627\u0631\u06cc\u0648\u06cc <\/strong><strong>\u06f2: <\/strong><strong>&#8220;<\/strong><strong>\u06af\u0630\u0631 \u062a\u062f\u0631\u06cc\u062c\u06cc \u0647\u0645\u0631\u0627\u0647 \u0628\u0627 \u06a9\u0627\u0633\u062a\u06cc<\/strong><strong>&#8220;<\/strong><strong> (\u0648\u0627\u0642\u0639\u200c\u0628\u06cc\u0646\u0627\u0646\u0647)<\/strong><\/span><\/h3>\n<ul style=\"text-align: justify;\">\n<li><span style=\"color: #000000;\">\u062a\u0623\u0633\u06cc\u0633 \u0645\u0631\u06a9\u0632 \u0627\u0645\u0627 \u0628\u0627 \u0628\u0648\u062f\u062c\u0647 \u0648 \u0627\u062e\u062a\u06cc\u0627\u0631\u0627\u062a \u0645\u062d\u062f\u0648\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc HTA \u0641\u0642\u0637 \u0628\u0631\u0627\u06cc \u067e\u0631\u0647\u0632\u06cc\u0646\u0647\u200c\u062a\u0631\u06cc\u0646 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627 (\u0645\u0627\u0646\u0646\u062f \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0633\u0631\u0637\u0627\u0646 \u0648 \u0698\u0646 \u062f\u0631\u0645\u0627\u0646\u06cc) \u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u062a\u0635\u0645\u06cc\u0645\u0627\u062a \u0647\u0645\u0686\u0646\u0627\u0646 \u062a\u0627 \u062d\u062f\u06cc \u0633\u06cc\u0627\u0633\u06cc \u0648 \u063a\u06cc\u0631\u0634\u0641\u0627\u0641 \u0628\u0627\u0642\u06cc \u0645\u06cc\u200c\u0645\u0627\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0628\u0631\u062e\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0628\u0627 \u0627\u062b\u0631\u0628\u062e\u0634\u06cc \u0645\u062a\u0648\u0633\u0637 \u0627\u0645\u0627 \u0647\u0632\u06cc\u0646\u0647 \u0628\u0627\u0644\u0627\u060c \u0628\u062f\u0648\u0646 \u067e\u0648\u0634\u0634 \u0645\u06cc\u200c\u0645\u0627\u0646\u0646\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0646\u062a\u06cc\u062c\u0647:<\/strong>\u0628\u0647\u0628\u0648\u062f \u0646\u0633\u0628\u06cc \u0627\u0645\u0627 \u062a\u062f\u0627\u0648\u0645 \u0646\u0627\u0628\u0631\u0627\u0628\u0631\u06cc \u0648 \u0639\u062f\u0645 \u0628\u0647\u0631\u0647\u200c\u0648\u0631\u06cc \u06a9\u0627\u0645\u0644.<\/span><\/li>\n<\/ul>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0633\u0646\u0627\u0631\u06cc\u0648\u06cc <\/strong><strong>\u06f3: <\/strong><strong>&#8220;<\/strong><strong>\u0631\u06a9\u0648\u062f \u0648 \u0627\u0646\u0641\u0639\u0627\u0644<\/strong><strong>&#8220;<\/strong><strong> (\u0646\u0627\u0645\u0637\u0644\u0648\u0628)<\/strong><\/span><\/h3>\n<ul style=\"text-align: justify;\">\n<li><span style=\"color: #000000;\">\u0641\u0642\u062f\u0627\u0646 \u0627\u0631\u0627\u062f\u0647 \u0633\u06cc\u0627\u0633\u06cc \u0628\u0631\u0627\u06cc \u062a\u0623\u0633\u06cc\u0633 \u0646\u0647\u0627\u062f \u0645\u0633\u062a\u0642\u0644.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u062f\u0627\u0645\u0647 \u0648\u0636\u0639 \u0645\u0648\u062c\u0648\u062f: \u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u0645\u0648\u0631\u062f\u06cc\u060c \u063a\u06cc\u0631\u0634\u0641\u0627\u0641 \u0648 \u0641\u0627\u0642\u062f \u0634\u0648\u0627\u0647\u062f.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u0627\u0641\u0632\u0627\u06cc\u0634 \u0641\u0634\u0627\u0631 \u0645\u0627\u0644\u06cc \u0628\u0631 \u0628\u06cc\u0645\u0647\u200c\u0647\u0627 \u0628\u0647 \u062f\u0644\u06cc\u0644 \u0648\u0631\u0648\u062f \u0628\u06cc\u200c\u0631\u0648\u06cc\u0647 \u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u06af\u0631\u0627\u0646.<\/span><\/li>\n<li><span style=\"color: #000000;\">\u06a9\u0627\u0647\u0634 \u0627\u0639\u062a\u0645\u0627\u062f \u0639\u0645\u0648\u0645\u06cc \u0648 \u0641\u0631\u0627\u0631 \u0633\u0631\u0645\u0627\u06cc\u0647\u200c\u0647\u0627\u06cc \u0627\u0646\u0633\u0627\u0646\u06cc \u0628\u0647 \u062e\u0627\u0631\u062c.<\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0646\u062a\u06cc\u062c\u0647:<\/strong>\u0627\u0632 \u062f\u0633\u062a \u0631\u0641\u062a\u0646 \u0641\u0631\u0635\u062a \u062a\u0627\u0631\u06cc\u062e\u06cc \u0628\u0631\u0627\u06cc \u0631\u0647\u0628\u0631\u06cc \u0645\u0646\u0637\u0642\u0647\u200c\u0627\u06cc \u062f\u0631 \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc.<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><strong>\u062a\u0648\u0635\u06cc\u0647 \u0631\u0627\u0647\u0628\u0631\u062f\u06cc:<\/strong>\u00a0\u062d\u0631\u06a9\u062a \u0642\u0627\u0637\u0639 \u0628\u0647 \u0633\u0648\u06cc \u0633\u0646\u0627\u0631\u06cc\u0648\u06cc \u06f1 \u0628\u0627 \u0627\u062c\u0631\u0627\u06cc \u0645\u0631\u062d\u0644\u0647 \u0627\u0648\u0644 \u0646\u0642\u0634\u0647 \u0631\u0627\u0647.<\/span><\/p>\n<h2 style=\"text-align: justify;\"><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u0647\u0641\u062a\u0645: \u0645\u0644\u0627\u062d\u0638\u0627\u062a \u0627\u062e\u0644\u0627\u0642\u06cc \u0648 \u0639\u062f\u0627\u0644\u062a\u200c\u0645\u062d\u0648\u0631\u06cc \u062f\u0631<\/strong><strong> HTA <\/strong><strong>\u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc<\/strong><\/span><\/h2>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0646\u0638\u0627\u0645 HTA \u0635\u0631\u0641\u0627\u064b \u0627\u0628\u0632\u0627\u0631 \u0641\u0646\u06cc \u0648 \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0646\u06cc\u0633\u062a\u060c \u0628\u0644\u06a9\u0647 \u062d\u0627\u0645\u0644 \u0627\u0631\u0632\u0634\u200c\u0647\u0627\u06cc \u0627\u062e\u0644\u0627\u0642\u06cc \u0648 \u0627\u062c\u062a\u0645\u0627\u0639\u06cc \u0627\u0633\u062a. \u062f\u0631 \u0637\u0631\u0627\u062d\u06cc \u0622\u0646 \u0628\u0631\u0627\u06cc \u0627\u06cc\u0631\u0627\u0646\u060c \u0647\u0641\u062a \u0627\u0635\u0644 \u0628\u0627\u06cc\u062f \u0631\u0639\u0627\u06cc\u062a \u0634\u0648\u062f:<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0627\u0635\u0644 \u0627\u0648\u0644: \u0634\u0641\u0627\u0641\u06cc\u062a \u06a9\u0627\u0645\u0644<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u062a\u0645\u0627\u0645 \u0645\u0631\u0627\u062d\u0644 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc (\u0645\u0639\u06cc\u0627\u0631\u0647\u0627\u060c \u062f\u0627\u062f\u0647\u200c\u0647\u0627\u060c \u0645\u062f\u0644\u200c\u0647\u0627\u060c \u0641\u0631\u0636\u06cc\u0627\u062a \u0648 \u062a\u0636\u0627\u062f \u0645\u0646\u0627\u0641\u0639) \u0628\u0627\u06cc\u062f \u0628\u0647 \u0632\u0628\u0627\u0646 \u0633\u0627\u062f\u0647 \u0628\u0631\u0627\u06cc \u0639\u0645\u0648\u0645 \u0645\u0646\u062a\u0634\u0631 \u0634\u0648\u062f.<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0627\u0635\u0644 \u062f\u0648\u0645: \u0645\u0634\u0627\u0631\u06a9\u062a \u0630\u06cc\u200c\u0646\u0641\u0639\u0627\u0646<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0628\u06cc\u0645\u0627\u0631\u0627\u0646\u060c \u067e\u0632\u0634\u06a9\u0627\u0646\u060c \u062a\u0648\u0644\u06cc\u062f\u06a9\u0646\u0646\u062f\u06af\u0627\u0646 \u0648 \u0628\u06cc\u0645\u0647\u200c\u0634\u062f\u06af\u0627\u0646 \u0628\u0627\u06cc\u062f \u062f\u0631 \u0641\u0631\u0622\u06cc\u0646\u062f \u0627\u0648\u0644\u0648\u06cc\u062a\u200c\u0628\u0646\u062f\u06cc \u0648 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0645\u0634\u0627\u0631\u06a9\u062a \u062f\u0627\u0634\u062a\u0647 \u0628\u0627\u0634\u0646\u062f. \u062c\u0644\u0633\u0627\u062a \u0627\u0633\u062a\u0645\u0627\u0639 \u0639\u0645\u0648\u0645\u06cc \u0628\u0631\u06af\u0632\u0627\u0631 \u0634\u0648\u062f.<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0627\u0635\u0644 \u0633\u0648\u0645: \u0639\u062f\u0627\u0644\u062a \u062f\u0631 \u062a\u0648\u0632\u06cc\u0639<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0641\u0646\u0627\u0648\u0631\u06cc\u200c\u0647\u0627\u06cc \u0634\u062e\u0635\u06cc\u200c\u0634\u062f\u0647 \u0646\u0628\u0627\u06cc\u062f \u0641\u0642\u0637 \u0628\u0647 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u062b\u0631\u0648\u062a\u0645\u0646\u062f \u062f\u0631 \u062a\u0647\u0631\u0627\u0646 \u0628\u0631\u0633\u062f. HTA \u0628\u0627\u06cc\u062f \u062a\u0623\u062b\u06cc\u0631 \u0628\u0631 \u0646\u0627\u0628\u0631\u0627\u0628\u0631\u06cc\u200c\u0647\u0627\u06cc \u0645\u0646\u0637\u0642\u0647\u200c\u0627\u06cc \u0648 \u0627\u0642\u062a\u0635\u0627\u062f\u06cc \u0631\u0627 \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u06a9\u0646\u062f \u0648 \u067e\u0648\u0634\u0634 \u0631\u0627 \u0645\u062a\u0646\u0627\u0633\u0628 \u0628\u0627 \u0622\u0646 \u062a\u0646\u0638\u06cc\u0645 \u0646\u0645\u0627\u06cc\u062f.<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0627\u0635\u0644 \u0686\u0647\u0627\u0631\u0645: \u0627\u0648\u0644\u0648\u06cc\u062a \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc \u0646\u0627\u062f\u0631 \u0648 \u06a9\u0648\u062f\u06a9\u0627\u0646<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc\u06cc \u0628\u0627 \u0634\u06cc\u0648\u0639 \u0628\u0633\u06cc\u0627\u0631 \u067e\u0627\u06cc\u06cc\u0646 \u0648 \u0628\u062f\u0648\u0646 \u062f\u0631\u0645\u0627\u0646 \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646\u060c \u0622\u0633\u062a\u0627\u0646\u0647 ICER \u0627\u0646\u0639\u0637\u0627\u0641\u200c\u067e\u0630\u06cc\u0631\u062a\u0631 (\u062a\u0627 \u06f5 \u0628\u0631\u0627\u0628\u0631 GDP) \u0642\u0627\u0628\u0644 \u0642\u0628\u0648\u0644 \u0627\u0633\u062a.<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0627\u0635\u0644 \u067e\u0646\u062c\u0645: \u0645\u0646\u0639 \u062a\u0628\u0639\u06cc\u0636 \u0698\u0646\u062a\u06cc\u06a9\u06cc<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u0646\u062a\u0627\u06cc\u062c \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc HTA \u0646\u0628\u0627\u06cc\u062f \u0645\u0646\u062c\u0631 \u0628\u0647 \u0645\u062d\u062f\u0648\u062f\u06cc\u062a \u067e\u0648\u0634\u0634 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0631 \u0627\u0633\u0627\u0633 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u0698\u0646\u062a\u06cc\u06a9\u06cc \u0634\u0648\u062f (\u0645\u062b\u0644\u0627\u064b \u0635\u0631\u0641\u0627\u064b \u0628\u0647 \u0627\u06cc\u0646 \u062f\u0644\u06cc\u0644 \u06a9\u0647 \u06cc\u06a9 \u0628\u06cc\u0648\u0645\u0627\u0631\u06a9\u0631 \u0646\u0627\u062f\u0631 \u062f\u0627\u0631\u0646\u062f).<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0627\u0635\u0644 \u0634\u0634\u0645: \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u062a\u0623\u062b\u06cc\u0631 \u0627\u062c\u062a\u0645\u0627\u0639\u06cc<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u067e\u06cc\u0634 \u0627\u0632 \u062a\u0635\u0645\u06cc\u0645 \u0646\u0647\u0627\u06cc\u06cc\u060c \u0627\u062b\u0631\u0627\u062a \u0627\u062c\u062a\u0645\u0627\u0639\u06cc (\u0645\u0627\u0646\u0646\u062f \u0627\u0633\u062a\u06cc\u06af\u0645\u0627\u060c \u0641\u0634\u0627\u0631 \u0631\u0648\u0627\u0646\u06cc \u0628\u0631 \u062e\u0627\u0646\u0648\u0627\u062f\u0647\u060c \u06cc\u0627 \u062a\u0634\u0648\u06cc\u0642 \u0628\u0647 \u0622\u0632\u0645\u0627\u06cc\u0634\u0627\u062a \u063a\u06cc\u0631\u0636\u0631\u0648\u0631\u06cc) \u0628\u0631\u0631\u0633\u06cc \u0634\u0648\u062f.<\/span><\/p>\n<h3 style=\"text-align: justify;\"><span style=\"font-size: 12pt; color: #000000;\"><strong>\u00a0<\/strong><strong>\u0627\u0635\u0644 \u0647\u0641\u062a\u0645: \u067e\u0627\u0633\u062e\u06af\u0648\u06cc\u06cc \u0648 \u0628\u0627\u0632\u0646\u06af\u0631\u06cc<\/strong><\/span><\/h3>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u062a\u0635\u0645\u06cc\u0645\u0627\u062a HTA \u0628\u0627\u06cc\u062f \u0642\u0627\u0628\u0644 \u0627\u0639\u062a\u0631\u0627\u0636 \u0648 \u062a\u062c\u062f\u06cc\u062f\u0646\u0638\u0631 \u0628\u0627\u0634\u0646\u062f. \u0647\u0631 \u06f3 \u0633\u0627\u0644 \u06cc\u06a9 \u0628\u0627\u0631\u060c \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc\u200c\u0647\u0627\u06cc \u0642\u0628\u0644\u06cc \u0645\u062c\u062f\u062f\u0627\u064b \u0628\u0631\u0631\u0633\u06cc \u0634\u0648\u0646\u062f.<\/span><\/p>\n<h2><span style=\"font-size: 14pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u0647\u0634\u062a\u0645: \u0646\u062a\u06cc\u062c\u0647\u200c\u06af\u06cc\u0631\u06cc \u0648 \u062a\u0648\u0635\u06cc\u0647\u200c\u0647\u0627\u06cc \u0633\u06cc\u0627\u0633\u062a\u06cc \u0646\u0647\u0627\u06cc\u06cc<\/strong><\/span><\/h2>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u06cc\u06a9 \u062a\u062d\u0648\u0644 \u0627\u062c\u062a\u0646\u0627\u0628\u200c\u0646\u0627\u067e\u0630\u06cc\u0631 \u0627\u0633\u062a\u060c \u0627\u0645\u0627 \u0628\u062f\u0648\u0646 \u0646\u0638\u0627\u0645 \u0634\u0641\u0627\u0641 \u0648 \u0645\u0628\u062a\u0646\u06cc \u0628\u0631 \u0634\u0648\u0627\u0647\u062f \u00a0HTA\u060c \u0627\u06cc\u0646 \u062a\u062d\u0648\u0644 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u0628\u0647 \u062c\u0627\u06cc \u06a9\u0627\u0647\u0634 \u0646\u0627\u0628\u0631\u0627\u0628\u0631\u06cc\u060c \u0622\u0646 \u0631\u0627 \u062a\u0634\u062f\u06cc\u062f \u06a9\u0646\u062f \u0648 \u0645\u0646\u0627\u0628\u0639 \u0645\u062d\u062f\u0648\u062f \u0646\u0638\u0627\u0645 \u0633\u0644\u0627\u0645\u062a \u0627\u06cc\u0631\u0627\u0646 \u0631\u0627 \u0628\u0647 \u0647\u062f\u0631 \u062f\u0647\u062f.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">\u062a\u062d\u0644\u06cc\u0644 \u0648\u0636\u0639\u06cc\u062a \u0645\u0648\u062c\u0648\u062f \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0627\u06cc\u0631\u0627\u0646 \u0627\u0632 \u0646\u0638\u0631 \u0646\u0647\u0627\u062f\u06cc\u060c \u0631\u0648\u0634\u200c\u0634\u0646\u0627\u062e\u062a\u06cc\u060c \u062f\u0627\u062f\u0647\u200c\u0627\u06cc \u0648 \u0646\u06cc\u0631\u0648\u06cc \u0627\u0646\u0633\u0627\u0646\u06cc \u062f\u0631 \u062d\u0648\u0632\u0647 HTA \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u0628\u0627\u00a0<strong>\u0634\u06a9\u0627\u0641\u200c\u0647\u0627\u06cc \u0639\u0645\u06cc\u0642<\/strong>\u00a0\u0645\u0648\u0627\u062c\u0647 \u0627\u0633\u062a. \u0627\u0645\u0627 \u062a\u062c\u0627\u0631\u0628 \u0645\u0648\u0641\u0642 \u06a9\u0634\u0648\u0631\u0647\u0627\u06cc\u06cc \u0628\u0627 \u062f\u0631\u0622\u0645\u062f \u0645\u0634\u0627\u0628\u0647 (\u0645\u0627\u0646\u0646\u062f \u0633\u0646\u06af\u0627\u067e\u0648\u0631\u060c \u062a\u0631\u06a9\u06cc\u0647 \u0648 \u0645\u0627\u0644\u0632\u06cc) \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0628\u0627\u00a0<strong>\u0627\u0631\u0627\u062f\u0647 \u0633\u06cc\u0627\u0633\u06cc\u060c \u0633\u0631\u0645\u0627\u06cc\u0647\u200c\u06af\u0630\u0627\u0631\u06cc \u0647\u062f\u0641\u0645\u0646\u062f \u0648 \u0647\u0645\u06a9\u0627\u0631\u06cc \u0628\u06cc\u0646\u200c\u0627\u0644\u0645\u0644\u0644\u06cc<\/strong>\u060c \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u062f\u0631 \u0645\u062f\u062a \u06f5 \u0633\u0627\u0644 \u0646\u0638\u0627\u0645 \u06a9\u0627\u0631\u0622\u0645\u062f\u06cc \u0627\u06cc\u062c\u0627\u062f \u06a9\u0631\u062f. \u067e\u0632\u0634\u06a9\u06cc \u0634\u062e\u0635\u06cc \u0628\u062f\u0648\u0646 \u00a0HTA\u060c \u0645\u0627\u0646\u0646\u062f \u0646\u0627\u0648\u0628\u0631\u06cc \u062f\u0631 \u062f\u0631\u06cc\u0627\u06cc \u0637\u0648\u0641\u0627\u0646\u06cc \u0628\u062f\u0648\u0646 \u0642\u0637\u0628\u200c\u0646\u0645\u0627\u0633\u062a. \u0628\u0627 \u0627\u0633\u062a\u0642\u0631\u0627\u0631 \u0646\u0638\u0627\u0645 HTA \u0647\u0648\u0634\u0645\u0646\u062f\u060c \u0634\u0641\u0627\u0641 \u0648 \u0639\u0627\u062f\u0644\u0627\u0646\u0647\u060c \u0627\u06cc\u0631\u0627\u0646 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u0636\u0645\u0646 \u0635\u06cc\u0627\u0646\u062a \u0627\u0632 \u062d\u0642\u0648\u0642 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0648 \u0645\u0646\u0627\u0628\u0639 \u0639\u0645\u0648\u0645\u06cc\u060c \u0628\u0647 \u06cc\u06a9\u06cc \u0627\u0632 \u0628\u0627\u0632\u06cc\u06af\u0631\u0627\u0646 \u0627\u0635\u0644\u06cc \u0645\u0646\u0637\u0642\u0647 \u062f\u0631 \u062d\u0648\u0632\u0647 \u067e\u0632\u0634\u06a9\u06cc \u0641\u0631\u0627\u062f\u0642\u06cc\u0642 \u062a\u0628\u062f\u06cc\u0644 \u0634\u0648\u062f. \u0632\u0645\u0627\u0646 \u0627\u0642\u062f\u0627\u0645\u060c \u0627\u0645\u0631\u0648\u0632 \u0627\u0633\u062a.<\/span><\/p>\n<h2><span style=\"font-size: 12pt; color: #000000;\"><strong>\u0641\u0635\u0644 \u0646\u0647\u0645: \u0645\u0646\u0627\u0628\u0639 \u0648 \u0645\u0631\u0627\u062c\u0639<\/strong><\/span><\/h2>\n<ol>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0National Institute for Health and Care Excellence (NICE). (2024). Guide to the methods of technology appraisal. London: NICE.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0CADTH. (2023). Guidelines for the economic evaluation of health technologies: Canada. Ottawa: CADTH.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0IQWiG. (2022). General methods for the assessment of the relation of benefits to costs. Cologne: IQWiG.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0Pharmaceutical Benefits Advisory Committee (PBAC). (2023). Guidelines for preparing submissions to the PBAC. Canberra: Australian Government.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0World Health Organization. (2021). Health technology assessment (HTA) for personalized medicine: a scoping review. Geneva: WHO.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0Garrison, L. P., &amp; Towse, A. (2017). Value-based pricing and reimbursement in personalised healthcare. <em>Journal of Personalized Medicine<\/em>, 7(3), 10.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0Husereau, D., Drummond, M., &amp; Petrou, S. (2022). Consolidated Health Economic Evaluation Reporting Standards (CHEERS) 2022 statement. <em>BMJ<\/em>, 376, e067975.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0Neumann, P. J., &amp; Cohen, J. T. (2018). QALYs in 2018\u2014advantages and concerns. <em>JAMA<\/em>, 319(24), 2473-2474.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0O\u2019Rourke, B., Oortwijn, W., &amp; Schuller, T. (2020). The new definition of health technology assessment. <em>International Journal of Technology Assessment in Health Care<\/em>, 36(3), 187-190.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0Akbari Sari, A., &amp; Olyaeemanesh, A. (2019). Health technology assessment in Iran: challenges and opportunities. <em>Medical Journal of the Islamic Republic of Iran<\/em>, 33, 56.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0Doshmangir, L., et al. (2020). Policy analysis of health technology assessment in Iran. <em>Health Research Policy and Systems<\/em>, 18(1), 1-12.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">Iran Think Tanks Society. (2019). Research and activities of Iranian think tanks. Retrieved from\u00a0<a style=\"color: #000000;\" href=\"https:\/\/iranthinktanks.com\/\">https:\/\/iranthinktanks.com\/<\/a><\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0Karimi Esboei, S., Ghazinoory, S., &amp; Saghafi, F. (2025). A national framework for transition to precision medicine. <em>Frontiers in Medicine<\/em>, 11, 1396496.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0World Bank. (2025). GDP per capita (current US$) \u2013 Iran. World Bank Data.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0NICE International. (2023). Supporting health technology assessment in middle-income countries: a partnership guide.<\/span><\/li>\n<li style=\"text-align: left;\"><span style=\"color: #000000;\">\u00a0PerMedHTA Project. (2022). Recommendations for HTA of personalised medicine. EU Horizon 202<\/span>0.<\/li>\n<\/ol>\n<p><span style=\"color: #000080; font-size: 14pt;\"><strong>\u0628\u0631\u0627\u06cc \u062f\u0631\u06cc\u0627\u0641\u062a \u0641\u0627\u06cc\u0644 \u06a9\u0627\u0645\u0644 \u0645\u0642\u0627\u0644\u0647 \u06a9\u0644\u06cc\u06a9 \u06a9\u0646\u06cc\u062f.<\/strong><\/span><\/p>\n<p><span style=\"color: #ff0000;\"><strong><a style=\"color: #ff0000;\" href=\"https:\/\/abtaab.ir\/wp-content\/uploads\/2026\/08\/\u0646\u0638\u0627\u0645-\u0645\u0644\u06cc-\u0627\u0631\u0632\u06cc\u0627\u0628\u06cc-\u0641\u0646\u0627\u0648\u0631\u06cc-\u0633\u0644\u0627\u0645\u062a-.pdf\">\u0646\u0638\u0627\u0645 \u0645\u0644\u06cc \u0627\u0631\u0632\u06cc\u0627\u0628\u06cc \u0641\u0646\u0627\u0648\u0631\u06cc \u0633\u0644\u0627\u0645\u062a<\/a><\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0622\u0628\u062a\u0627\u0628: \u0627\u0646\u062f\u06cc\u0634\u06a9\u062f\u0647 \u0639\u0644\u0645\u06cc \u062a\u062d\u0642\u06cc\u0642\u0627\u062a\u06cc 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